NFL best bets today: Week 6 picks include Titans vs. Raiders play [10/12/2025]

Today’s NFL picks for October 12, 2025 are here, with Sunday’s NFL best bets fueled by tens of thousands of predictive simulations analyzing the latest odds and matchups.

These NFL best bets include matchups like the Titans vs. Raiders game at 4:05PM ET, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge NFL bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Sunday, October 12, 2025, including our complete set of picks and best bets for today and the week ahead.

List of NFL best bets today [10/12, updated 4:04PM ET]

After diving deep into the numbers and conducting thousands of simulations, our famous predictive analytics model has figured out the best football bet for Sunday, October 12, 2025.

Titans +3.5 (-105)

• Probability: 58.9%
• Edge: 7.7%
• Matchup: Titans vs. Raiders (4:05PM ET, Sunday)

Our model has pinpointed a high-probability NFL betting opportunity today, which comes in the Titans vs. Raiders matchup. We recommend a spread bet on Titans +3.5 at -105 odds, with our analysis showing a 58.9% chance of hitting and a compelling edge of 7.7%.

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Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for October 12, 2025.

List of upcoming NFL games to bet on [10/12/2025]

• Titans vs. Raiders (4:05PM ET, Sunday)
• 49ers vs. Buccaneers (4:25PM ET, Sunday)
• Bengals vs. Packers (4:25PM ET, Sunday)
• Lions vs. Chiefs (8:20PM ET, Sunday)

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More on NFL

The bets on this page form part of our NFL player props and NFL best bets series.

For more NFL betting content, we have NFL trends for every game, as well as daily NFL betting news and the latest Super Bowl odds and predictions.

Conclusion

Our NFL best bets are locked and loaded for October 12, 2025, featuring plays such as Titans +3.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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