NFL best bets today: Week 16 picks include Eagles vs. Commanders play [12/20/2025]

Today’s NFL picks for December 20, 2025 are here, with Eagles vs. Commanders among the top plays identified by our model across Saturday’s NFL schedule.

Dimers’ predictive analytics engine runs 24/7, going over the latest football odds to find real betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NFL best bets today [12/20, updated 4:37PM ET]

Below, you’ll find today’s top 10 football bets, ranked by edge for Saturday, December 20, 2025.

Commanders +7 (+100)

• Edge: 7.0%
• Probability: 57%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

Our model has identified value on Commanders +7 at +100 odds. A 57% probability produces an edge of 7.0%, making this the strongest play for today's NFL slate.

Eagles vs. Commanders over 43.5 points (-110)

• Edge: 5.8%
• Probability: 58.2%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

Eagles vs. Commanders over 43.5 points carries a 5.8% edge and a probability of 58.2% at -110 odds, according to our model.

Commanders ML (+315)

• Edge: 5.7%
• Probability: 29.8%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

Commanders ML at +315 odds shows a 5.7% edge, supported by a 29.8% probability in simulations.

Commanders +7 (+100)

• Edge: 7.0%
• Probability: 57%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

A 7.0% edge and 57% probability make Commanders +7 vs. Eagles at a value play in the Eagles vs. Commanders matchup, per our model.

Jets +6.5 (-110)

• Edge: 5.9%
• Probability: 58.3%
• Matchup: Jets vs. Saints (1:00PM ET, Sunday)

Jets +6.5 at -110 odds presents a 5.9% edge, with simulations resulting in a probability of 58.3%.

Eagles vs. Commanders over 43.5 points (-110)

• Edge: 5.8%
• Probability: 58.2%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

Our model finds value on over 43.5 points in Eagles vs. Commanders at -110 odds, supported by an edge of 5.8%.

Commanders ML (+315)

• Edge: 5.7%
• Probability: 29.8%
• Matchup: Eagles vs. Commanders (5:00PM ET, Saturday)

Our model has uncovered value on Commanders ML at +315 odds. A 29.8% probability produces a 5.7% edge, making this a strong play for today's NFL action.

Jaguars +3 (-105)

• Edge: 5.2%
• Probability: 56.5%
• Matchup: Jaguars vs. Broncos (4:05PM ET, Sunday)

A 5.2% edge on a 56.5% probability makes Jaguars +3 at -105 odds a solid value play in today's Jaguars vs. Broncos matchup.

Steelers ML (+275)

• Edge: 2.9%
• Probability: 29.5%
• Matchup: Steelers vs. Lions (4:25PM ET, Sunday)

Our model projects value on Steelers to win at +275 odds. A 29.5% probability produces a 2.9% edge, making Steelers the favorable ML play in Saturday’s matchup.

Steelers +7 (+100)

• Edge: 2.7%
• Probability: 52.7%
• Matchup: Steelers vs. Lions (4:25PM ET, Sunday)

Rounding out our top 10 bets, Steelers +7 at +100 odds shows a 52.7% probability and a 2.7% edge.

NFL best bets summary: Saturday, 12/20/2025

As of 4:37PM ET, here are our top NFL bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Eagles vs. Commanders	Commanders +7	+100 @ DraftKings	7.0%	57%
Eagles vs. Commanders	Over 43.5 Points	-110 @ DraftKings	5.8%	58.2%
Eagles vs. Commanders	Commanders ML	+315 @ FanDuel	5.7%	29.8%
Eagles vs. Commanders	Commanders +7	+100 @ DraftKings	7.0%	57%
Jets vs. Saints	Jets +6.5	-110 @ BetMGM	5.9%	58.3%
Eagles vs. Commanders	Over 43.5 Points	-110 @ DraftKings	5.8%	58.2%
Eagles vs. Commanders	Commanders ML	+315 @ FanDuel	5.7%	29.8%
Jaguars vs. Broncos	Jaguars +3	-105 @ BetMGM	5.2%	56.5%
Steelers vs. Lions	Steelers ML	+275 @ DraftKings	2.9%	29.5%
Steelers vs. Lions	Steelers +7	+100 @ DraftKings	2.7%	52.7%

List of upcoming NFL games to bet on [12/20/2025]

• Eagles vs. Commanders (5:00PM ET, Saturday)
• Packers vs. Bears (8:20PM ET, Saturday)
• Bills vs. Browns (1:00PM ET, Sunday)
• Chargers vs. Cowboys (1:00PM ET, Sunday)
• Jets vs. Saints (1:00PM ET, Sunday)
• Buccaneers vs. Panthers (1:00PM ET, Sunday)
• Vikings vs. Giants (1:00PM ET, Sunday)
• Chiefs vs. Titans (1:00PM ET, Sunday)
• Bengals vs. Dolphins (1:00PM ET, Sunday)
• Jaguars vs. Broncos (4:05PM ET, Sunday)
• Falcons vs. Cardinals (4:05PM ET, Sunday)
• Raiders vs. Texans (4:25PM ET, Sunday)
• Steelers vs. Lions (4:25PM ET, Sunday)

AI betting support with Dimebot

Learn how Dimebot uses Dimers’ data to deliver quick answers and insights, helping you make faster, more informed decisions.

NFL betting promos for Week 16

Make the most of our best bets today—including Commanders +7—with the two offers listed below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket.

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.

Conclusion

Our NFL best bets are locked and loaded for December 20, 2025, featuring plays such as Commanders +7 and over 43.5 points also in the Eagles vs. Commanders matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.