Yankees vs. Orioles prediction: Yankees favored to win Wednesday's MLB matchup [5/13/2026]
Get New York Yankees vs Baltimore Orioles predictions for MLB Wednesday.

The Baltimore Orioles will take on the New York Yankees in MLB action at Oriole Park at Camden Yards on Wednesday, starting at 1:05 PM ET.
Kyle Bradish (1-5, 4.83 ERA) will start on the mound for the Orioles, up against Max Fried (4-2, 2.92 ERA) for the Yankees.
Based on the latest simulations, Dimers' advanced MLB model predicts the Yankees as the most likely winner of the Yankees vs. Orioles game.
This article offers further insights into Wednesday's matchup, including best bets and picks.
Yankees vs. Orioles prediction: Who will win and cover?
Our independent predictive model gives the Yankees a 59% chance of defeating the Orioles.
According to our model, the Orioles (+1.5) have a 53% chance of covering the run line, while the over/under total of nine runs has a 53% chance of going over.
Yankees vs. Orioles odds [5/13/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Yankees | Orioles |
|---|---|---|
| Run Line | -1.5 (-102) | +1.5 (-110) |
| Moneyline | -166 | +140 |
| Total | o9 (-102) | u9 (-118) |
All odds are correct at the time of publication and are subject to change.
Yankees vs. Orioles picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Orioles +1.5 | -110 |
| Moneyline | Orioles | +140 |
| Total | Over 9 | -102 |
According to our MLB best bets, the top play to make on this game is Over 9 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Yankees vs. Orioles game-day updates and essential details
Wednesday's MLB game between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to begin at 1:05 PM ET.
- Who: New York Yankees vs. Baltimore Orioles
- Date: Wednesday, May 13, 2026
- Time: 1:05 PM ET/10:05AM PT
- Venue: Oriole Park at Camden Yards
Conclusion
We predict the Yankees, with a 59% win probability, will likely beat the Orioles in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



