Mets vs. Padres prediction: San Diego favored to win Friday's MLB matchup [6/5/2026]
Get New York Mets vs San Diego Padres predictions for MLB Friday.

MLB action continues on Friday at 9:40 PM ET as the New York Mets take on the San Diego Padres at Petco Park.
Michael King (4-4, 3.18 ERA) will get the ball for the Padres, while the Mets are going with Christian Scott (1-0, 2.97 ERA).
Based on the latest simulations, Dimers' advanced MLB model projects the Padres as the most likely winner of the Mets vs. Padres game.
This article offers an expanded analysis of Friday's matchup, including best bets and picks.
Mets vs. Padres prediction: Who will win and cover?
Our famous predictive model gives the Padres a 52.4% chance of beating the Mets.
According to our model, the Mets (+1.5) have a 65.7% chance of covering the run line, while the over/under total of 7.5 runs has a 50.7% chance of staying under.
Mets vs. Padres odds [6/5/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Mets | Padres |
|---|---|---|
| Run Line | +1.5 (-200) | -1.5 (+168) |
| Moneyline | +110 | -126 |
| Total | o7.5 (+104) | u7.5 (-128) |
All odds are correct at the time of publication and are subject to change.
Mets vs. Padres picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Mets +1.5 | -200 |
| Moneyline | Mets | +110 |
| Total | Over 7.5 | +104 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Mets vs. Padres game-day updates and essential details
Friday's MLB matchup between the Padres and Mets at Petco Park is scheduled to commence at 9:40 PM ET.
- Who: New York Mets vs. San Diego Padres
- Date: Friday, June 5, 2026
- Time: 9:40 PM ET/6:40PM PT
- Venue: Petco Park
Conclusion
We predict the Padres, with a 52.4% win probability, will likely beat the Mets in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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