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Knicks vs. Spurs prediction: San Antonio to win, Jalen Brunson projected for 30 points in Wednesday's NBA game [12/31/2025]

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Written by Jason Bevilacqua

Get New York Knicks vs San Antonio Spurs predictions for NBA Wednesday.

New York Knicks-San Antonio Spurs Predictions and Game Preview.
New York Knicks vs. San Antonio Spurs NBA prediction for Wednesday, December 31, 2025.

The San Antonio Spurs and New York Knicks will lock horns in NBA action at Frost Bank Center on Wednesday, with tipoff at 7:00 PM ET.

Based on the latest simulations and today’s injury news, Dimers' advanced NBA model predicts the Spurs as the most likely winner of the Knicks vs. Spurs game.

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like Victor Wembanyama, De'Aaron Fox and Stephon Castle, while the Knicks will rely on Jalen Brunson, Karl-Anthony Towns and OG Anunoby.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Knicks vs. Spurs prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Knicks and Spurs 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Spurs a 58% chance of beating the Knicks. Our predicted final score has the Spurs winning 118-116.

According to our model, the Spurs (-1.5) have a 52% chance of covering the spread, while the 235.5-point over/under has a 52% chance of staying under.

 

Knicks vs. Spurs odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Knicks Spurs
Spread +1.5 (-110) -1.5 (-110)
Moneyline +102 -118
Total o235.5 (-115) u235.5 (-105)

All odds are correct at the time of publication and are subject to change.

Knicks vs. Spurs picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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