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Giants vs. Patriots prediction: New England favored to win MNF Week 13, 2025

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Written by Dave Garofolo

Get New York Giants vs New England Patriots predictions for NFL Monday.

New York Giants-New England Patriots Predictions and Game Preview.
New York Giants vs. New England Patriots NFL prediction for Monday, December 1, 2025.

The New England Patriots and New York Giants will meet in Week 13 of the NFL season at Gillette Stadium on Monday, starting at 8:15PM ET.

Based on the latest simulation results, Dimers' proven NFL model predicts the Patriots as the most likely winner of the Giants vs. Patriots game.

This article offers a closer look at this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Giants vs. Patriots prediction: Who will win and cover?

Since our Giants-Patriots predictions earlier in the week, we have simulated the result of Monday's NFL matchup between the Giants and Patriots 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Patriots a 74% chance of defeating the Giants in Week 13 of the NFL season. Our predicted final score has the Patriots winning 26-19.

According to our model, the bookies have got it right, and the Giants and Patriots each have a 50% chance of covering the spread, while the 46.5-point over/under also has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 13 straight up picks.

Giants vs. Patriots odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Giants Patriots
Spread +7.5 (-122) -7.5 (+100)
Moneyline +295 -350
Total o46.5 (-110) u46.5 (-105)

All odds are correct at the time of publication and are subject to change.

Giants vs. Patriots picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Patriots -7.5 +100
Moneyline Giants +295
Total Under 46.5 -105

According to our NFL best bets, the top play to make on this game is Giants to win.

 

Giants vs. Patriots TD scorers

Who will score a touchdown in Giants vs. Patriots?

According to our list of touchdown scorer predictions for MNF, TreVeyon Henderson is most likely to score an anytime TD in Giants vs. Patriots.

Our projections give Henderson a 48.1% chance of scoring a TD at Gillette Stadium, while the running back is an 11.4% chance of registering the first touchdown the game.

Anytime touchdown scorer predictions

New York Giants

Player Anytime TD Probability
Jaxson Dart (QB) 32.4%
Devin Singletary (RB) 30.2%
Wan'Dale Robinson (WR) 28.3%
Tyrone Tracy (RB) 24.8%
Theo Johnson (TE) 24.5%

New England Patriots

Player Anytime TD Probability
TreVeyon Henderson (RB) 48.1%
Stefon Diggs (WR) 37.1%
Rhamondre Stevenson (RB) 30.0%
Hunter Henry (TE) 29.4%
Kayshon Boutte (WR) 25.7%

First touchdown scorer predictions

New York Giants

Player First TD Probability
Jaxson Dart (QB) 6.7%
Devin Singletary (RB) 6.1%
Wan'Dale Robinson (WR) 5.7%
Tyrone Tracy (RB) 4.9%
Theo Johnson (TE) 4.8%

New England Patriots

Player First TD Probability
TreVeyon Henderson (RB) 11.4%
Stefon Diggs (WR) 8.1%
Rhamondre Stevenson (RB) 6.2%
Hunter Henry (TE) 6.1%
Kayshon Boutte (WR) 5.2%

Giants vs Patriots player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Giants and Patriots. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 13 games.

Quarterbacks

Of the starting quarterbacks, the Giants' Jaxson Dart is projected for 211 passing yards. The Patriots' Drake Maye is expected to throw for 246 yards.

Player Proj. Pass Yards
Jaxson Dart (NYG) 211
Drake Maye (NE) 246

Giants rushing

Player Proj. Rush Yards
Tyrone Tracy 49
Jaxson Dart 31
Devin Singletary 31

Patriots rushing

Player Proj. Rush Yards
TreVeyon Henderson 65
Rhamondre Stevenson 29
Drake Maye 26

Giants receiving

Player Proj. Rec. Yards
Wan'Dale Robinson 63
Theo Johnson 37
Darius Slayton 36
Isaiah Hodgins 30
Tyrone Tracy 21

Patriots receiving

Player Proj. Rec. Yards
Stefon Diggs 57
Hunter Henry 41
Kayshon Boutte 38
Mack Hollins 38
DeMario Douglas 22

Giants vs. Patriots game-day updates and essential details

The NFL Week 13 action between the Patriots and Giants at Gillette Stadium is scheduled to start at 8:15PM ET.

 

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Conclusion

We predict the Patriots, with a 74% win probability, will likely beat the Giants in Week 13 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Patriots insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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