Omaha vs. South Dakota prediction: Nebraska-Omaha favored to win men's college basketball matchup [3/6/2026]

South Dakota will square off with Omaha in men's college basketball action at Denny Sanford Premier Center on Friday, commencing at 7:00 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Nebraska-Omaha as the most likely winner of the Omaha vs. South Dakota game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Omaha vs. South Dakota prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Friday's NCAA basketball matchup between Omaha and South Dakota 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Nebraska-Omaha a 60% chance of beating South Dakota. Our predicted final score has Nebraska-Omaha winning 78-75.

According to our model, Nebraska-Omaha (-2.5) has a 55% chance of covering the spread, while the over/under total of 151.5 points has a 54% chance of going over.

Omaha vs. South Dakota odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Omaha	South Dakota
Spread	-2.5 (-102)	+2.5 (-120)
Moneyline	-134	+114
Total	o151.5 (-110)	u151.5 (-110)

All odds are correct at the time of publication and are subject to change.

Omaha vs. South Dakota picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Nebraska-Omaha -2.5	-102
Moneyline	Nebraska-Omaha	-134
Total	Over 151.5	-110

According to our men's college basketball best bets, the top play to make on this game is Nebraska-Omaha -2.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Omaha vs. South Dakota game-day updates and essential details

Friday's men's college basketball action between South Dakota and Omaha at Denny Sanford Premier Center is scheduled to begin at 7:00 PM ET.

• Who: Nebraska-Omaha vs. South Dakota
• Date: Friday, March 6, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Denny Sanford Premier Center

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Conclusion

We predict Nebraska-Omaha, with a 60% win probability, will likely beat South Dakota on Friday.

AI and automation have enhanced this article to quickly deliver accurate Nebraska-Omaha vs. South Dakota insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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