May 23, 2026
Portland Timbers vs. San Jose Earthquakes prediction, odds, MLS picks [5/23/2026]
Read Article MLS betting tips: Saturday's picks include Houston vs. LA Galaxy play [5/23/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get MLS betting tips and picks for Saturday, May 23, 2026.
Today’s MLS betting tips for May 23, 2026 are here, with Houston vs. LA Galaxy and New England vs. Charlotte among the top plays identified by our model across Saturday’s MLS action.
Dimers’ predictive analytics engine runs 24/7, scanning the latest soccer odds to unearth top betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.
List of MLS betting tips tonight [5/23, updated 1:03PM ET]
Below, you’ll find today’s best soccer bets, ranked by edge for Saturday, May 23, 2026.
LA Galaxy ML (+115)
- Edge: 3.9%
- Probability: 50.4%
- Matchup: Houston vs. LA Galaxy (10:30PM ET, Saturday)
Our model has identified value on LA Galaxy to defeat Houston at +115 odds. A 50.4% probability produces an edge of 3.9%, making this the strongest play for today's MLS slate.
Charlotte ML (-106)
- Edge: 3.4%
- Probability: 54.9%
- Matchup: New England vs. Charlotte (7:30PM ET, Saturday)
Charlotte ML carries a 3.4% edge and a probability of 54.9% at -106 odds, according to our model.
Nashville ML (-135)
- Edge: 3.3%
- Probability: 60.8%
- Matchup: NY City vs. Nashville (8:30PM ET, Saturday)
Nashville ML at -135 odds shows a 3.3% edge, supported by a 60.8% probability in simulations.
San Diego FC ML (+250)
- Edge: 2.7%
- Probability: 31.3%
- Matchup: Vancouver vs. San Diego FC (9:30PM ET, Saturday)
A 2.7% edge and 31.3% probability make San Diego FC at the moneyline at a value play in the Vancouver vs. San Diego FC matchup, per our model.
NY City vs. Nashville over 2.5 goals (-120)
- Edge: 2.7%
- Probability: 57.3%
- Matchup: NY City vs. Nashville (8:30PM ET, Saturday)
NY City vs. Nashville over 2.5 goals at -120 odds presents a 2.7% edge, with simulations resulting in a probability of 57.3%.
Colorado ML (+125)
- Edge: 2.0%
- Probability: 46.5%
- Matchup: Dallas vs. Colorado (9:30PM ET, Saturday)
Our model finds value on Colorado to win at +125 odds, supported by an edge of 2.0%.
MLS best bets summary: Saturday, 5/23/2026
As of 1:03PM ET, here are our top MLS bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Houston vs. LA Galaxy | LA Galaxy ML | +115 @ FanDuel | 3.9% | 50.4% |
| New England vs. Charlotte | Charlotte ML | -106 @ BetRivers | 3.4% | 54.9% |
| NY City vs. Nashville | Nashville ML | -135 @ BetMGM | 3.3% | 60.8% |
| Vancouver vs. San Diego FC | San Diego FC ML | +250 @ Caesars | 2.7% | 31.3% |
| NY City vs. Nashville | Over 2.5 Goals | -120 @ Caesars | 2.7% | 57.3% |
| Dallas vs. Colorado | Colorado ML | +125 @ BetMGM | 2.0% | 46.5% |
List of upcoming MLS games to bet on [5/23/2026]
- Austin vs. St Louis City (2:45PM ET, Saturday)
- Salt Lake vs. Minnesota (4:30PM ET, Saturday)
- Orlando vs. Cincinnati (7:30PM ET, Saturday)
- Montreal vs. D.C. United (7:30PM ET, Saturday)
- New England vs. Charlotte (7:30PM ET, Saturday)
- Toronto vs. Chicago (8:30PM ET, Saturday)
- NY Red Bulls vs. Sporting KC (8:30PM ET, Saturday)
- NY City vs. Nashville (8:30PM ET, Saturday)
- Dallas vs. Colorado (9:30PM ET, Saturday)
- Vancouver vs. San Diego FC (9:30PM ET, Saturday)
- San Jose vs. Portland (9:30PM ET, Saturday)
- Houston vs. LA Galaxy (10:30PM ET, Saturday)
Conclusion
Our MLS best bets are locked and loaded for May 23, 2026, featuring plays such as LA Galaxy ML and Charlotte ML. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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