MLB player props today: Wednesday's best props include Didier Fuentes [4/22/2026]

Dimers' MLB props are live for April 22, 2026, with today's top prop bets led by the likes of Didier Fuentes, Shohei Ohtani and Walker Buehler.

Our MLB player props model runs continuously, analyzing every matchup, including White Sox vs. D-Backs and Yankees vs. Red Sox, to surface the best MLB player prop bets across the market—including those identified by our new MLB Sweet Spot tool.

List of MLB prop picks for Wednesday, 4/22

Sourced from 70+ total props today, below are the top ten MLB player props for April 22, ranked by probability.

Didier Fuentes under 5.5 hits allowed (-163)

• Edge: 9.5%
• Probability: 71.4%
• Game: Braves vs. Nationals (6:45PM ET)

Our model has flagged value on Atlanta's Didier Fuentes under 5.5 hits allowed. A probability of 71.4% gives this play an edge of 9.5% at -163 odds.

Didier Fuentes under 4.5 strikeouts (-152)

• Edge: 9.4%
• Probability: 69.7%
• Game: Braves vs. Nationals (6:45PM ET)

Didier Fuentes’s strikeouts prop shows a 69.7% probability and an 9.4% edge at -152 odds, according to our model.

Shohei Ohtani under 4.5 hits allowed (-146)

• Edge: 8.6%
• Probability: 69.6%
• Game: Dodgers vs. Giants (9:45PM ET)

The data highlights value on Shohei Ohtani under 4.5 hits allowed, with simulations showing a 69.6% probability and an 8.6% edge at -146.

Walker Buehler over 2.5 earned runs (-140)

• Edge: 7.9%
• Probability: 66.2%
• Game: Padres vs. Rockies (8:40PM ET)

Our model finds value on Walker Buehler over 2.5 earned runs, with a 66.2% probability and an edge of 7.9% at -140 odds.

Walker Buehler over 5.5 hits allowed (-123)

• Edge: 9.5%
• Probability: 65.2%
• Game: Padres vs. Rockies (8:40PM ET)

Simulations indicate value on Walker Buehler over 5.5 hits allowed for San Diego, showing an edge of 9.5% at -123 odds.

Anthony Kay over 14.5 outs recorded (-127)

• Edge: 9.1%
• Probability: 65.1%
• Game: White Sox vs. D-Backs (9:40PM ET)

Anthony Kay’s outs recorded prop shows an edge of 9.1% at -127 odds, supported by a 65.1% probability according to our model.

Miguel Andujar over 1.5 bases (-120)

• Edge: 9.2%
• Probability: 63.7%
• Game: Padres vs. Rockies (8:40PM ET)

Our model highlights value on Miguel Andujar over 1.5 bases for San Diego, with a 63.7% probability and a 9.2% edge at -120 odds.

Braxton Ashcraft over 1.5 walks allowed (-138)

• Edge: 5.6%
• Probability: 63.6%
• Game: Pirates vs. Rangers (8:05PM ET)

The data shows value on Braxton Ashcraft over 1.5 walks allowed, supported by a 63.6% probability at -138 odds and an edge of 5.6%.

Clay Holmes over 1.5 earned runs (-125)

• Edge: 7.6%
• Probability: 63.2%
• Game: Twins vs. Mets (7:10PM ET)

A 7.6% edge on the over 1.5 earned runs line makes Clay Holmes a value play in Twins vs. Mets, supported by a 63.2% probability at -125 odds.

Mark Vientos to get a hit (-144)

• Edge: 2.8%
• Probability: 61.8%
• Game: Twins vs. Mets (7:10PM ET)

Simulations show value on Mark Vientos to get a hit here, with a 61.8% probability and 2.8% edge at -144 odds.

MLB player prop summary: Wednesday, April 22, 2026

A quick summary of today’s top props by probability according to our model as of 5:57PM ET:

Conclusion

For April 22, 2026, our MLB prop bets feature players such as Didier Fuentes, Shohei Ohtani and Walker Buehler. Each pick is grounded in real-time data and advanced simulations to help you bet with clarity and purpose.

Built using automation and human oversight, this article draws on the latest data to deliver accurate, timely insights. If using this article for betting, Dimers promotes responsible gambling.