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Missouri vs. Mississippi State prediction: Why Missouri is favored to win men's college basketball matchup [2/28/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Missouri vs Mississippi State predictions for college basketball Saturday.
Mississippi State will square off with Missouri, in what is expected to be a close men's college basketball game, at Humphrey Coliseum on Saturday, starting at 1:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model gives Missouri a slight edge with a 51% win probability over Mississippi State.
This article offers further insights into Saturday's Missouri vs. Mississippi State matchup, including an expanded look at the predicted score, best bets and picks.
Missouri vs. Mississippi State prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Missouri and Mississippi State 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Missouri a 51% chance of beating Mississippi State. Our predicted score is Missouri 78-78 Mississippi State.
According to our model, Mississippi State (+1.5) has a 55% chance of covering the spread, while the over/under total of 155.5 points has a 52% chance of going over.
While there is no way for a men's college basketball game to end in a tie, our prediction of 78-78 is based on each team's average score in the above-mentioned simulations of Missouri vs. Mississippi State.
Missouri vs. Mississippi State odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Missouri | Mississippi State |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-108) |
| Moneyline | -125 | +106 |
| Total | o155.5 (-105) | u155.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Missouri vs. Mississippi State picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Mississippi State +1.5 | -108 |
| Moneyline | Mississippi State | +106 |
| Total | Over 155.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Mississippi State +1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Missouri vs. Mississippi State game-day updates and essential details
Saturday's men's college basketball game between Mississippi State and Missouri at Humphrey Coliseum is scheduled to commence at 1:00 PM ET.
- Who: Missouri vs. Mississippi State
- Date: Saturday, February 28, 2026
- Time: 1:00 PM ET/10:00AM PT
- Venue: Humphrey Coliseum
Conclusion
We predict Missouri, with a 51% win probability, will likely beat Mississippi State on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Missouri vs. Mississippi State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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