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Mississippi State vs. Alabama prediction: Why Alabama is favored to win men's college basketball matchup [2/25/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Mississippi State vs Alabama predictions for college basketball Wednesday.
Men's college basketball action continues on Wednesday at 9:00 PM ET as Mississippi State looks to defy the odds against Alabama in men's college basketball action at Coleman Coliseum.
Based on the latest simulations, Dimers' proven college basketball model projects Alabama as the most likely winner of the Mississippi State vs. Alabama game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Mississippi State vs. Alabama prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Mississippi State and Alabama 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Alabama an 87% chance of defeating Mississippi State. Our predicted final score has Alabama winning 90-77.
According to our model, Alabama (-12.5) has a 54% chance of covering the spread, while the over/under total of 175.5 points has a 53% chance of staying under.
Mississippi State vs. Alabama odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Mississippi State | Alabama |
|---|---|---|
| Spread | +12.5 (-102) | -12.5 (-110) |
| Moneyline | +700 | -900 |
| Total | o175.5 (-115) | u175.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Mississippi State vs. Alabama picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Alabama -12.5 | -110 |
| Moneyline | Mississippi State | +700 |
| Total | Under 175.5 | -105 |
According to our best men's college basketball bets, the top play to make on this game is Under 175.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Mississippi State vs. Alabama game-day updates and essential details
Wednesday's men's college basketball action between Alabama and Mississippi State at Coleman Coliseum is scheduled to begin at 9:00 PM ET.
- Who: Mississippi State vs. Alabama
- Date: Wednesday, February 25, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Coleman Coliseum
Conclusion
We predict Alabama, with an 87% win probability, will likely beat Mississippi State on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Mississippi State vs. Alabama insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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