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Michigan State vs. Ole Miss prediction: Ole Miss favored to win women's college basketball matchup [12/22/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Michigan State vs Ole Miss predictions for college basketball Monday.
Women's college basketball action continues on Monday at 7:30 PM ET as Michigan State squares off with Ole Miss at Harrah's Cherokee Casino.
Based on the latest simulations, Dimers' new women's basketball model predicts Ole Miss as the most likely winner of the Michigan State vs. Ole Miss game.
This article offers a closer look at Monday's matchup, including best bets and picks.
Michigan State vs. Ole Miss prediction: Who will win?
Using powerful machine learning and data, we have simulated the result of Monday's women's basketball matchup between Michigan State and Ole Miss 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model gives Ole Miss a 72% chance of defeating Michigan State.
According to our model, the 144.5-point over/under has a 51% chance of staying under.
Michigan State vs. Ole Miss odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Michigan State | Ole Miss |
|---|---|---|
| Spread | +2.5 (-110) | -2.5 (-110) |
| Moneyline | +128 | -142 |
| Total | o144.5 (-110) | u144.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Michigan State vs. Ole Miss picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Ole Miss -2.5 | -110 |
| Moneyline | Ole Miss | -142 |
| Total | Under 144.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Ole Miss to win.
Michigan State vs. Ole Miss game-day updates and essential details
Monday's women's basketball matchup between Ole Miss and Michigan State at Harrah's Cherokee Casino is scheduled to begin at 7:30 PM ET.
- Who: Michigan State vs. Ole Miss
- Date: Monday, December 22, 2025
- Time: 7:30 PM ET/4:30PM PT
- Venue: Harrah's Cherokee Casino
Conclusion
We predict Ole Miss, with a 72% win probability, will likely beat Michigan State on Monday.
AI and automation have enhanced this article to quickly deliver accurate Michigan State vs. Ole Miss insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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