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Michigan State vs. Ole Miss prediction: Ole Miss favored to win women's college basketball matchup [12/22/2025]

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Written by Ryan Leaver

Get Michigan State vs Ole Miss predictions for college basketball Monday.

Michigan State-Ole Miss Predictions and Game Preview.
Michigan State vs. Ole Miss women's college basketball prediction for Monday, December 22, 2025.

Ole Miss will take on Michigan State in women's college basketball action at Harrah's Cherokee Casino on Monday, beginning at 7:30 PM ET.

Based on updated simulation results, Dimers' new women's basketball model predicts Ole Miss as the most likely winner of the Michigan State vs. Ole Miss game.

This article offers further insights into Monday's matchup, including best bets and picks.

Michigan State vs. Ole Miss prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Monday's women's basketball matchup between Michigan State and Ole Miss 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model gives Ole Miss a 72% chance of defeating Michigan State.

According to our model, the over/under total of 143.5 points has a 51% chance of staying under.

 

Michigan State vs. Ole Miss odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Michigan State Ole Miss
Spread +3.5 (-114) -3.5 (-114)
Moneyline +136 -168
Total o143.5 (-114) u143.5 (-114)

All odds are correct at the time of publication and are subject to change.

Michigan State vs. Ole Miss picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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