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Miami (FL) vs. Purdue prediction: Why Purdue is favored to win men's March Madness Second Round matchup [3/22/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Miami (FL) vs Purdue predictions for college basketball Sunday.
Men's college basketball action continues on Sunday at 12:10 PM ET as Miami (FL) takes on the favored Purdue in Second Round action at Enterprise Center.
For this Second Round matchup, Purdue—a veteran group led by the winningest senior class in school history— face Miami (FL), one of the biggest turnarounds in college basketball.
Based on the latest simulation results, Dimers' advanced college basketball model predicts Purdue as the most likely winner of the Miami (FL) vs. Purdue game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Miami (FL) vs. Purdue prediction: Who will win and advance to the Sweet Sixteen?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's NCAAM Tournament game between Miami (FL) and Purdue 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Purdue a 79% chance of beating Miami (FL). Our predicted final score has Purdue winning 78-70.
According to our model, Purdue (-8.5) has a 51% chance of covering the spread, while the 147.5-point over/under has a 53% chance of going over.
Miami (FL) vs. Purdue odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Miami (FL) | Purdue |
|---|---|---|
| Spread | +8.5 (-118) | -8.5 (-102) |
| Moneyline | +300 | -350 |
| Total | o147.5 (-105) | u147.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Miami (FL) vs. Purdue picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Purdue -8.5 | -102 |
| Moneyline | Purdue | -350 |
| Total | Over 147.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 147.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Miami (FL) vs. Purdue game-day updates and essential details
Sunday's men's college basketball action between Purdue and Miami (FL) at Enterprise Center is scheduled to commence at 12:10 PM ET.
- Who: Miami (FL) vs. Purdue
- Date: Sunday, March 22, 2026
- Time: 12:10 PM ET/9:10AM PT
- Venue: Enterprise Center
- March Madness stage: Second Round
College basketball betting and fantasy promos and codes
Make the most of Dimers' Miami (FL) vs. Purdue predictions by exploring the below offers from OG, Bet365, BetMGM, and Thrillzz.
Conclusion
We predict Purdue, with a 79% win probability, will likely beat Miami (FL) this men's March Madness Second Round matchup.
AI and automation have enhanced this article to quickly deliver accurate Miami (FL) vs. Purdue insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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