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Louisville vs. Notre Dame prediction: Notre Dame favored to win women's college basketball matchup [1/15/2026]
Get Louisville vs Notre Dame predictions for college basketball Thursday.

Notre Dame will square off with Louisville in women's college basketball action at Purcell Pavilion on Thursday, starting at 6:00 PM ET.
Based on updated simulation results, Dimers' new women's basketball model predicts Notre Dame as the most likely winner of the Louisville vs. Notre Dame game.
This article offers a closer look at Thursday's matchup, including best bets and picks.
Louisville vs. Notre Dame prediction: Who will win?
Using powerful machine learning and data analysis, we have simulated the result of Thursday's women's basketball game between Louisville and Notre Dame 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model gives Notre Dame a 79% chance of defeating Louisville.
According to our model, the over/under total of 148.5 points has a 57% chance of staying under.
Louisville vs. Notre Dame odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Louisville | Notre Dame |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-110) |
| Moneyline | -125 | +112 |
| Total | o148.5 (-110) | u148.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Louisville vs. Notre Dame picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Notre Dame +1.5 | -110 |
| Moneyline | Notre Dame | +112 |
| Total | Under 148.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Notre Dame to win.
Louisville vs. Notre Dame game-day updates and essential details
Thursday's women's basketball action between Notre Dame and Louisville at Purcell Pavilion is scheduled to start at 6:00 PM ET.
- Who: Louisville vs. Notre Dame
- Date: Thursday, January 15, 2026
- Time: 6:00 PM ET/3:00PM PT
- Venue: Purcell Pavilion
Conclusion
We predict Notre Dame, with a 79% win probability, will likely beat Louisville on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Notre Dame insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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