Los Angeles Rams vs. Seattle Seahawks: Experts release early Week 16 projections [2025]

The Los Angeles Rams and Seattle Seahawks will meet in Week 16 of the NFL season at Lumen Field on Thursday, December 18, 2025, starting at 8:15PM ET.

Initial simulations from Dimers' trusted NFL model favor the Seahawks as the most likely winner of this NFC West rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Rams vs. Seahawks predictions page.

LA Rams vs. Seattle early predictions

Leveraging trusted machine learning and analysis, we have simulated the Rams vs. Seahawks game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Rams 44%, Seahawks 56%
• Predicted final score: Rams 23-24 Seahawks
• Spread: Rams (-1.5) 45%, Seahawks (+1.5) 55%
• Total points (46.5): Over 57%, Under 43%

As of December 15, 2025, these Rams-Seahawks calculations and predictions reflect the latest data and insights available.

Rams vs. Seahawks Week 16 details

The NFL Week 16 action between the Seahawks and Rams at Lumen Field is scheduled for December 18, 2025.

• Who: Los Angeles Rams vs. Seattle Seahawks
• Date: Thursday, December 18, 2025
• Time: 8:15PM ET/5:15PM PT
• Venue: Lumen Field

Rams vs. Seahawks opening odds

We've researched the best betting odds across America for this Week 16 game, which are listed here:

• Spread: Rams -1.5 (-102), Seahawks +1.5 (-120)
• Moneyline: Rams -108, Seahawks -106
• Total: Over/Under 46.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Seahawks, with a 56% win probability, will likely beat the Rams in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Rams vs. Seahawks matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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