Rams vs. Panthers prediction: Why Rams are favored to win in NFL Week 13, 2025

The Carolina Panthers will face the favored Los Angeles Rams in NFL Week 13 action at Bank of America Stadium on Sunday, commencing at 1:00PM ET.

Based on the latest simulation results, Dimers' advanced NFL model predicts the Rams as the most likely winner of the Rams vs. Panthers game.

This article offers a closer look at Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Rams vs. Panthers prediction: Who will win and cover?

Since our Rams-Panthers predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Rams and Panthers 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Rams an 80% chance of beating the Panthers in Week 13 of the NFL season. Our predicted final score has the Rams winning 26-17.

According to our model, the Panthers (+10) have a 54% chance of covering the spread, while the over/under total of 44.5 points has an equal 50-50 chance of hitting.

To see win probabilities for every matchup this week, check out our expert NFL Week 13 straight up picks.

Rams vs. Panthers odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Rams	Panthers
Spread	-10 (-110)	+10 (-105)
Moneyline	-560	+425
Total	o44.5 (-115)	u44.5 (-104)

All odds are correct at the time of publication and are subject to change.

Rams vs. Panthers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Panthers +10	-105
Moneyline	Panthers	+425
Total	Under 44.5	-104

According to our NFL best bets, the top play to make on this game is Panthers +10 at the spread.

Rams vs. Panthers TD scorers

Who will score a touchdown in Rams vs. Panthers?

According to our list of touchdown scorer predictions for Week 13, Davante Adams is most likely to score an anytime touchdown in Rams vs. Panthers.

Our projections give Adams a 53.0% chance of scoring a TD at Bank of America Stadium, while the wide receiver is a 13.3% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Los Angeles Rams

Player	Anytime TD Probability
Davante Adams (WR)	53.0%
Kyren Williams (RB)	50.6%
Puka Nacua (WR)	42.8%
Blake Corum (RB)	26.3%
Colby Parkinson (TE)	23.1%

Carolina Panthers

Player	Anytime TD Probability
Rico Dowdle (RB)	37.8%
Tetairoa McMillan (WR)	31.8%
Xavier Legette (WR)	18.6%
Jalen Coker (WR)	17.2%
Ja'Tavion Sanders (TE)	12.1%

First touchdown scorer predictions

Los Angeles Rams

Player	First TD Probability
Davante Adams (WR)	13.3%
Kyren Williams (RB)	12.4%
Puka Nacua (WR)	9.8%
Blake Corum (RB)	5.4%
Colby Parkinson (TE)	4.6%

Carolina Panthers

Player	First TD Probability
Rico Dowdle (RB)	9.7%
Tetairoa McMillan (WR)	7.8%
Xavier Legette (WR)	4.2%
Jalen Coker (WR)	3.9%
Ja'Tavion Sanders (TE)	2.7%

Rams vs Panthers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Rams and Panthers. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 13 games.

Quarterbacks

Of the starting quarterbacks, the Rams' Matthew Stafford is projected to have a big game with 265 passing yards, while the Panthers' Bryce Young is expected to throw for 200 yards.

Player	Proj. Pass Yards
Matthew Stafford (LA)	265
Bryce Young (CAR)	200

Rams rushing

Player	Proj. Rush Yards
Kyren Williams	68
Blake Corum	39
Puka Nacua	4

Panthers rushing

Player	Proj. Rush Yards
Rico Dowdle	63
Chuba Hubbard	20
Bryce Young	12

Rams receiving

Player	Proj. Rec. Yards
Puka Nacua	95
Davante Adams	63
Colby Parkinson	27
Terrance Ferguson	19
Davis Allen	16

Panthers receiving

Player	Proj. Rec. Yards
Tetairoa McMillan	63
Jalen Coker	34
Xavier Legette	29
Ja'Tavion Sanders	21
Rico Dowdle	20

Rams vs. Panthers game-day updates and essential details

The NFL Week 13 action between the Panthers and Rams at Bank of America Stadium is scheduled to begin at 1:00PM ET.

• Who: Los Angeles Rams vs. Carolina Panthers
• Date: Sunday, November 30, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Bank of America Stadium

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Conclusion

We predict the Rams, with an 80% win probability, will likely beat the Panthers in Week 13 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Rams vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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