Rams vs. Cardinals prediction: Why Rams are favored to win in NFL Week 14, 2025

NFL Week 14 action continues on Sunday at 4:25PM ET as the Los Angeles Rams take on the Arizona Cardinals at State Farm Stadium.

Based on updated simulation results, Dimers' proven NFL model predicts the Rams as the most likely winner of the Rams vs. Cardinals game.

This article offers a closer look at this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Rams vs. Cardinals prediction: Who will win and cover?

Since our Rams-Cardinals predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Rams and Cardinals 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the Rams a 78% chance of beating the Cardinals in Week 14 of the NFL season. Our predicted final score has the Rams winning 28-20.

According to our model, the Cardinals (+9.5) have a 53% chance of covering the spread, while the 49.5-point over/under has a 52% chance of staying under.

To see win probabilities for every matchup this week, check out our expert NFL Week 14 straight up picks.

Rams vs. Cardinals odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Rams	Cardinals
Spread	-9.5 (-110)	+9.5 (-110)
Moneyline	-485	+410
Total	o49.5 (-110)	u49.5 (-110)

All odds are correct at the time of publication and are subject to change.

Rams vs. Cardinals picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Cardinals +9.5	-110
Moneyline	Cardinals	+410
Total	Under 49.5	-110

According to our NFL best bets, the top play to make on this game is Cardinals to win.

Rams vs. Cardinals TD scorers

Who will score a touchdown in Rams vs. Cardinals?

According to our list of touchdown scorer predictions for Week 14, Davante Adams is most likely to score an anytime TD in Rams vs. Cardinals.

Our projections give Adams a 55.5% chance of scoring a TD at State Farm Stadium, while the wide receiver is a 13.4% chance of registering the first touchdown the game.

Anytime touchdown scorer predictions

Los Angeles Rams

Player	Anytime TD Probability
Davante Adams (WR)	55.5%
Kyren Williams (RB)	50.5%
Puka Nacua (WR)	44.1%
Blake Corum (RB)	28.2%
Colby Parkinson (TE)	23.8%

Arizona Cardinals

Player	Anytime TD Probability
Trey McBride (TE)	39.2%
Bam Knight (RB)	38.8%
Michael Wilson (WR)	31.3%
Michael Carter (RB)	18.1%
Andre Baccellia (WR)	13.0%

First touchdown scorer predictions

Los Angeles Rams

Player	First TD Probability
Davante Adams (WR)	13.4%
Kyren Williams (RB)	11.7%
Puka Nacua (WR)	9.6%
Blake Corum (RB)	5.5%
Colby Parkinson (TE)	4.5%

Arizona Cardinals

Player	First TD Probability
Trey McBride (TE)	8.8%
Bam Knight (RB)	8.7%
Michael Wilson (WR)	6.6%
Michael Carter (RB)	3.5%
Andre Baccellia (WR)	2.5%

Rams vs Cardinals player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Rams and Cardinals. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 14 games.

Quarterbacks

Of the starting quarterbacks, the Rams' Matthew Stafford is projected to have a big game with 269 passing yards, while the Cardinals' Jacoby Brissett is expected to throw for 255 yards.

Player	Proj. Pass Yards
Matthew Stafford (LA)	269
Jacoby Brissett (ARI)	255

Rams rushing

Player	Proj. Rush Yards
Kyren Williams	69
Blake Corum	41
Puka Nacua	4

Cardinals rushing

Player	Proj. Rush Yards
Bam Knight	41
Michael Carter	23
Jacoby Brissett	15

Rams receiving

Player	Proj. Rec. Yards
Puka Nacua	95
Davante Adams	63
Colby Parkinson	29
Xavier Smith	21
Terrance Ferguson	16

Cardinals receiving

Player	Proj. Rec. Yards
Michael Wilson	75
Trey McBride	75
Andre Baccellia	28
Michael Carter	20
Elijah Higgins	19

Rams vs. Cardinals game-day updates and essential details

The NFL Week 14 game between the Cardinals and Rams at State Farm Stadium is scheduled to start at 4:25PM ET.

• Who: Los Angeles Rams vs. Arizona Cardinals
• Date: Sunday, December 7, 2025
• Time: 4:25PM ET/1:25PM PT
• Venue: State Farm Stadium

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Conclusion

We predict the Rams, with a 78% win probability, will likely beat the Cardinals in Week 14 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Rams vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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