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Chargers vs. Dolphins prediction: Why Chargers are favored to win in NFL Week 6, 2025

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Written by Dave Garofolo

Get Los Angeles Chargers vs Miami Dolphins predictions for NFL Sunday.

Los Angeles Chargers-Miami Dolphins Predictions and Game Preview.
Los Angeles Chargers vs. Miami Dolphins NFL prediction for Sunday, October 12, 2025.

NFL Week 6 action continues on Sunday at 1:00PM ET as the Los Angeles Chargers take on the Miami Dolphins at Hard Rock Stadium.

Based on the latest simulations, Dimers' proven NFL model predicts the Chargers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Chargers-Dolphins game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Chargers with a win probability of 63%, while the Dolphins have 37%."

This gameday Chargers vs. Dolphins betting preview builds on my Chargers vs. Dolphins prediction that was released earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Chargers vs. Dolphins predictions page.

Chargers vs. Dolphins predictions

Since our Chargers-Dolphins predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Chargers and Dolphins 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Chargers a 63% chance of beating the Dolphins in Week 6 of the NFL season. Our predicted final score has the Chargers winning 24-20.

According to our model, the bookmakers have got it right, and the Chargers and Dolphins each have a 50% chance of covering the spread, while the over/under total of 45.5 points also has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 6 straight up picks.

Chargers vs. Dolphins odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Chargers Dolphins
Spread -3.5 (-102) +3.5 (-115)
Moneyline -180 +155
Total o45.5 (-110) u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Chargers vs. Dolphins picks and best bets

Our model's biggest edge in today's Chargers vs. Dolphins matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Chargers vs. Dolphins TD scorers

Who will score the first touchdown in Chargers vs. Dolphins?

According to our list of touchdown scorer predictions for Week 6, Miami's De'Von Achane is most likely to score the first touchdown in Chargers vs. Dolphins.

Our projections give Achane a 14.6% chance of scoring the first TD at Hard Rock Stadium, while the Dolphins running back is a 53.4% chance of registering an anytime touchdown.

First touchdown scorer predictions

Los Angeles Chargers

Player First TD Probability
Keenan Allen (WR) 9.2%
Hassan Haskins (RB) 8.7%
Ladd McConkey (WR) 8.7%

Miami Dolphins

Player First TD Probability
De'Von Achane (RB) 14.6%
Jaylen Waddle (WR) 7.5%
Darren Waller (TE) 5.7%

Anytime touchdown scorer predictions

Los Angeles Chargers

Player Anytime TD Probability
Keenan Allen (WR) 36.1%
Hassan Haskins (RB) 34.6%
Ladd McConkey (WR) 34.5%

Miami Dolphins

Player Anytime TD Probability
De'Von Achane (RB) 53.4%
Jaylen Waddle (WR) 32.6%
Darren Waller (TE) 25.9%

Chargers vs Dolphins player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Chargers and Dolphins. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our NFL player projections page now to access player prop projections for every offensive player in this matchup and all other Week 6 games.

Chargers vs. Dolphins quarterbacks

Of the starting quarterbacks, the Chargers' Justin Herbert is projected to throw for more yards than the Dolphins' Tua Tagovailoa.

Chargers rushing

Hassan Haskins, Kimani Vidal and Justin Herbert are projected to be the leading rushers for the Chargers.

Player Position
Hassan Haskins RB
Kimani Vidal RB
Justin Herbert QB

Dolphins rushing

De'Von Achane, Ollie Gordon and Tua Tagovailoa are expected to lead the Dolphins in rushing yards.

Player Position
De'Von Achane RB
Ollie Gordon RB
Tua Tagovailoa QB

Chargers receiving

Ladd McConkey, Keenan Allen, Tre' Harris, Oronde Gadsden and KeAndre Lambert-Smith are projected to top the receiving yards for the Chargers.

Player Position
Ladd McConkey WR
Keenan Allen WR
Tre' Harris WR
Oronde Gadsden TE
KeAndre Lambert-Smith WR

Dolphins receiving

Jaylen Waddle, Darren Waller, De'Von Achane, Malik Washington and Nick Westbrook-Ikhine are projected to lead the Dolphins in receiving yards.

Player Position
Jaylen Waddle WR
Darren Waller TE
De'Von Achane RB
Malik Washington WR
Nick Westbrook-Ikhine WR

Chargers vs. Dolphins game-day updates and essential details

The NFL Week 6 action between the Dolphins and Chargers at Hard Rock Stadium is scheduled to commence at 1:00PM ET.

Dimers' full preview of Sunday's Chargers vs. Dolphins matchup includes our prediction, picks and the latest betting odds.

Before making any Chargers vs. Dolphins picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Chargers, with a 63% win probability, will likely beat the Dolphins in Week 6 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Chargers vs. Dolphins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Stay up-to-date with the latest NFL news and NFL parlay picks throughout the season. Plus, our Super Bowl odds offer the latest probabilities for the Super Bowl, AFC, NFC and each division.

Boost your NFL betting by exploring the latest NFL betting promos, sourced from top sportsbooks and DFS operators.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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