Lafayette vs. Colgate prediction: Why Colgate is favored to win men's college basketball matchup [2/25/2026]

Men's college basketball action continues on Wednesday at 7:00 PM ET as Lafayette locks horns with Colgate in men's college basketball action at Cotterell Court.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Colgate as the most likely winner of the Lafayette vs. Colgate game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Lafayette vs. Colgate prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NCAA basketball game between Lafayette and Colgate 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Colgate an 80% chance of beating Lafayette. Our predicted final score has Colgate winning 78-69.

According to our model, Colgate (-8.5) has a 51% chance of covering the spread, while the over/under total of 148.5 points has a 53% chance of going over.

Lafayette vs. Colgate odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Lafayette vs. Colgate picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Over 148.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Lafayette vs. Colgate game-day updates and essential details

Wednesday's men's college basketball game between Colgate and Lafayette at Cotterell Court is scheduled to begin at 7:00 PM ET.

• Who: Lafayette vs. Colgate
• Date: Wednesday, February 25, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Cotterell Court

Conclusion

We predict Colgate, with an 80% win probability, will likely beat Lafayette on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Lafayette vs. Colgate insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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