Kentucky vs. South Carolina prediction: Kentucky favored to win men's college basketball matchup [2/24/2026]

Men's college basketball action continues on Tuesday at 7:00 PM ET as Kentucky takes on South Carolina in men's college basketball action at Colonial Life Arena.

Based on updated simulations, Dimers' advanced college basketball model projects Kentucky as the most likely winner of the Kentucky vs. South Carolina game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Kentucky vs. South Carolina prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Tuesday's NCAA basketball matchup between Kentucky and South Carolina 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Kentucky a 78% chance of defeating South Carolina. Our predicted final score has Kentucky winning 80-72.

According to our model, Kentucky (-3.5) has a 65% chance of covering the spread, while the over/under total of 153.5 points has a 54% chance of going over.

Kentucky vs. South Carolina odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Kentucky vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Kentucky to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Kentucky vs. South Carolina game-day updates and essential details

Tuesday's men's college basketball action between South Carolina and Kentucky at Colonial Life Arena is scheduled to begin at 7:00 PM ET.

• Who: Kentucky vs. South Carolina
• Date: Tuesday, February 24, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Colonial Life Arena

Conclusion

We predict Kentucky, with a 78% win probability, will likely beat South Carolina on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Kentucky vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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