James Madison vs. Southern Miss prediction: James Madison favored to win men's college basketball matchup [3/5/2026]

Southern Miss and James Madison will meet in men's college basketball action at Pensacola Bay Center on Thursday, starting at 6:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model projects James Madison as the most likely winner of the James Madison vs. Southern Miss game.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

James Madison vs. Southern Miss prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Thursday's NCAA basketball game between James Madison and Southern Miss 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives James Madison a 57% chance of defeating Southern Miss. Our predicted final score has James Madison winning 74-72.

According to our model, Southern Miss (+1.5) has a 56% chance of covering the spread, while the over/under total of 143.5 points has a 54% chance of going over.

James Madison vs. Southern Miss odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type	James Madison	Southern Miss
Spread	-1.5 (-120)	+1.5 (-102)
Moneyline	-140	+120
Total	o143.5 (-110)	u143.5 (-105)

All odds are correct at the time of publication and are subject to change.

James Madison vs. Southern Miss picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Southern Miss +1.5	-102
Moneyline	James Madison	-140
Total	Over 143.5	-110

According to our men's college basketball best bets, the top play to make on this game is Southern Miss +1.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

James Madison vs. Southern Miss game-day updates and essential details

Thursday's men's college basketball game between Southern Miss and James Madison at Pensacola Bay Center is scheduled to begin at 6:00 PM ET.

• Who: James Madison vs. Southern Miss
• Date: Thursday, March 5, 2026
• Time: 6:00 PM ET/3:00PM PT
• Venue: Pensacola Bay Center

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Conclusion

We predict James Madison, with a 57% win probability, will likely beat Southern Miss on Thursday.

AI and automation have enhanced this article to quickly deliver accurate James Madison vs. Southern Miss insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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