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Iowa vs. Florida prediction: Florida favored to win men's March Madness Second Round matchup [3/22/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Iowa vs Florida predictions for college basketball Sunday.
Florida will face Iowa in March Madness Second Round action at Benchmark International Arena on Sunday, starting at 7:10 PM ET.
For this Second Round clash, Florida—the defending national champions with a loaded returning frontcourt— face Iowa, a Ben McCollum team forcing plenty of turnovers.
Based on updated simulation results, Dimers' advanced college basketball model projects Florida as the most likely winner of the Iowa vs. Florida game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Iowa vs. Florida prediction: Who will win and advance to the Sweet Sixteen?
Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's NCAAM Tournament game between Iowa and Florida 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Florida an 86% chance of defeating Iowa. Our predicted final score has Florida winning 81-69.
According to our model, Florida (-10.5) has a 56% chance of covering the spread, while the over/under total of 145.5 points has a 58% chance of going over.
Iowa vs. Florida odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Iowa | Florida |
|---|---|---|
| Spread | +10.5 (-105) | -10.5 (-105) |
| Moneyline | +450 | -600 |
| Total | o145.5 (-108) | u145.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Iowa vs. Florida picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Florida -10.5 | -105 |
| Moneyline | Florida | -600 |
| Total | Over 145.5 | -108 |
According to our best men's college basketball bets, the top play to make on this game is Over 145.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Iowa vs. Florida game-day updates and essential details
Sunday's men's college basketball matchup between Florida and Iowa at Benchmark International Arena is scheduled to start at 7:10 PM ET.
- Who: Iowa vs. Florida
- Date: Sunday, March 22, 2026
- Time: 7:10 PM ET/4:10PM PT
- Venue: Benchmark International Arena
- March Madness stage: Second Round
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Make the most of Dimers' Iowa vs. Florida predictions by exploring the below offers from OG, Bet365, BetMGM, and Thrillzz.
Conclusion
We predict Florida, with an 86% win probability, will likely beat Iowa this men's March Madness Second Round matchup.
AI and automation have enhanced this article to quickly deliver accurate Iowa vs. Florida insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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