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Colts vs. Jaguars prediction: Indianapolis favored to win in NFL Week 14, 2025
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Indianapolis Colts vs Jacksonville Jaguars predictions for NFL Sunday.
NFL Week 14 action continues on Sunday at 1:00PM ET as the Indianapolis Colts take on the Jacksonville Jaguars at EverBank Stadium.
Based on the latest simulations, Dimers' advanced NFL model projects the Colts as the most likely winner of the Colts vs. Jaguars game.
This article offers an expanded analysis of this week's matchup, including projected touchdown scorers, best bets and player prop picks.
Colts vs. Jaguars prediction: Who will win and cover?
Since our Colts-Jaguars predictions earlier in the week, we have simulated the result of Sunday's NFL matchup between the Colts and Jaguars 10,000 times as part of our NFL predictions coverage.
Our independent predictive model currently gives the Colts a 57% chance of defeating the Jaguars in Week 14 of the NFL season. Our predicted final score has the Colts winning 23-21.
According to our model, the bookmakers have got it right, and the Colts and Jaguars each have a 50% chance of covering the spread, while the over/under total of 46 points has a 52% chance of staying under.
To see win probabilities for every matchup this week, check out our expert NFL Week 14 straight up picks.
Colts vs. Jaguars odds
We have researched the best NFL odds in America for this game, which are listed here:
| Bet Type | Colts | Jaguars |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-105) |
| Moneyline | -126 | +110 |
| Total | o46 (-110) | u46 (-110) |
All odds are correct at the time of publication and are subject to change.
Colts vs. Jaguars picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Jaguars +1.5 | -105 |
| Moneyline | Colts | -126 |
| Total | Under 46 | -110 |
According to our best NFL bets, the top play to make on this game is Colts to win.
Colts vs. Jaguars TD scorers
Who will score a touchdown in Colts vs. Jaguars?
According to our list of touchdown scorer predictions for Week 14, Jonathan Taylor is most likely to score an anytime touchdown in Colts vs. Jaguars.
Our projections give Taylor a 64.4% chance of getting in for six at EverBank Stadium, while the running back is an 18.3% chance of scoring the first touchdown the game.
Anytime touchdown scorer predictions
Indianapolis Colts
| Player | Anytime TD Probability |
|---|---|
| Jonathan Taylor (RB) | 64.4% |
| Tyler Warren (TE) | 30.8% |
| Michael Pittman (WR) | 29.0% |
| Alec Pierce (WR) | 26.7% |
| Josh Downs (WR) | 21.9% |
Jacksonville Jaguars
| Player | Anytime TD Probability |
|---|---|
| Travis Etienne (RB) | 39.7% |
| Bhayshul Tuten (RB) | 31.7% |
| Jakobi Meyers (WR) | 28.8% |
| Brian Thomas (WR) | 27.0% |
| Trevor Lawrence (QB) | 21.1% |
First touchdown scorer predictions
Indianapolis Colts
| Player | First TD Probability |
|---|---|
| Jonathan Taylor (RB) | 18.3% |
| Tyler Warren (TE) | 6.5% |
| Michael Pittman (WR) | 6.1% |
| Alec Pierce (WR) | 5.5% |
| Josh Downs (WR) | 4.4% |
Jacksonville Jaguars
| Player | First TD Probability |
|---|---|
| Travis Etienne (RB) | 8.8% |
| Bhayshul Tuten (RB) | 6.6% |
| Jakobi Meyers (WR) | 5.9% |
| Brian Thomas (WR) | 5.5% |
| Trevor Lawrence (QB) | 4.1% |
Colts vs Jaguars player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Colts and Jaguars. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 14 games.
Quarterbacks
Of the starting quarterbacks, the Colts' Daniel Jones is projected for 231 passing yards, while the Jaguars' Trevor Lawrence is expected to throw for 223 yards.
| Player | Proj. Pass Yards |
|---|---|
| Daniel Jones (IND) | 231 |
| Trevor Lawrence (JAX) | 223 |
Colts rushing
| Player | Proj. Rush Yards |
|---|---|
| Jonathan Taylor | 95 |
| Daniel Jones | 10 |
| Ameer Abdullah | 6 |
Jaguars rushing
| Player | Proj. Rush Yards |
|---|---|
| Travis Etienne | 54 |
| Bhayshul Tuten | 28 |
| Trevor Lawrence | 18 |
Colts receiving
| Player | Proj. Rec. Yards |
|---|---|
| Alec Pierce | 57 |
| Michael Pittman | 54 |
| Tyler Warren | 51 |
| Josh Downs | 39 |
| Jonathan Taylor | 20 |
Jaguars receiving
| Player | Proj. Rec. Yards |
|---|---|
| Jakobi Meyers | 58 |
| Brian Thomas | 48 |
| Brenton Strange | 46 |
| Parker Washington | 24 |
| Travis Etienne | 16 |
Colts vs. Jaguars game-day updates and essential details
The NFL Week 14 matchup between the Jaguars and Colts at EverBank Stadium is scheduled to start at 1:00PM ET.
- Who: Indianapolis Colts vs. Jacksonville Jaguars
- Date: Sunday, December 7, 2025
- Time: 1:00PM ET/10:00AM PT
- Venue: EverBank Stadium
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Conclusion
We predict the Colts, with a 57% win probability, will likely beat the Jaguars in Week 14 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Colts vs. Jaguars insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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