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Indiana State vs. Michigan State prediction: Why Michigan State is favored to win women's college basketball matchup [12/21/2025]

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Written by Ryan Leaver

Get Indiana State vs Michigan State predictions for college basketball Sunday.

Indiana State-Michigan State Predictions and Game Preview.
Indiana State vs. Michigan State women's college basketball prediction for Sunday, December 21, 2025.

Women's college basketball action continues on Sunday at 5:00 PM ET as Indiana State locks horns with Michigan State at Harrah's Cherokee Casino.

Based on the latest simulation results, Dimers' new women's basketball model projects Michigan State as the most likely winner of the Indiana State vs. Michigan State game.

This article offers a closer look at Sunday's matchup, including best bets and picks.

Indiana State vs. Michigan State prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Sunday's women's basketball matchup between Indiana State and Michigan State 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model gives Michigan State a 99% chance of defeating Indiana State.

According to our model, the 158.5-point over/under has a 52% chance of staying under.

 

Indiana State vs. Michigan State odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Indiana State Michigan State
Spread +51.5 (-114) -51.5 (-114)
Total o158.5 (-110) u158.5 (-110)

All odds are correct at the time of publication and are subject to change.

Indiana State vs. Michigan State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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