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Indiana State vs. Michigan State prediction: Why Michigan State is favored to win women's college basketball matchup [12/21/2025]

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Written by Ryan Leaver

Get Indiana State vs Michigan State predictions for college basketball Sunday.

Indiana State-Michigan State Predictions and Game Preview.
Indiana State vs. Michigan State women's college basketball prediction for Sunday, December 21, 2025.

Women's college basketball action continues on Sunday at 5:00 PM ET as Indiana State locks horns with Michigan State at Harrah's Cherokee Casino.

Based on the latest simulation results, Dimers' new women's basketball model projects Michigan State as the most likely winner of the Indiana State vs. Michigan State game.

This article offers a closer look at Sunday's matchup, including best bets and picks.

Indiana State vs. Michigan State prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Sunday's women's basketball matchup between Indiana State and Michigan State 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model gives Michigan State a 99% chance of defeating Indiana State.

According to our model, the 158.5-point over/under has a 52% chance of staying under.

 

Indiana State vs. Michigan State odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Indiana State Michigan State
Spread +51.5 (-114) -51.5 (-114)
Total o158.5 (-110) u158.5 (-110)

All odds are correct at the time of publication and are subject to change.

Indiana State vs. Michigan State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Indiana State +51.5 -114
Total Under 158.5 -110

According to our women's college basketball best bets, the top play to make on this game is Indiana State +51.5.

 

Indiana State vs. Michigan State game-day updates and essential details

Sunday's women's basketball game between Michigan State and Indiana State at Harrah's Cherokee Casino is scheduled to begin at 5:00 PM ET.

  • Who: Indiana State vs. Michigan State
  • Date: Sunday, December 21, 2025
  • Time: 5:00 PM ET/2:00PM PT
  • Venue: Harrah's Cherokee Casino

Conclusion

We predict Michigan State, with a 99% win probability, will likely beat Indiana State on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Indiana State vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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