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Read Article Illinois vs. Vanderbilt prediction: Vanderbilt favored to win women's March Madness Second Round matchup [3/23/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Illinois vs Vanderbilt predictions for college basketball Monday.
Vanderbilt will square off with Illinois in March Madness Second Round action at Memorial Gymnasium on Monday, commencing at 7:00 PM ET.
Based on updated simulation results, Dimers' new women's basketball model projects Vanderbilt as the most likely winner of the Illinois vs. Vanderbilt game.
This article offers a closer look at Monday's matchup, including best bets and picks.
Illinois vs. Vanderbilt prediction: Who will win and advance to the Sweet Sixteen?
Using innovative machine learning and statistical analysis, we have simulated the result of Monday's NCAAW Tournament matchup between Illinois and Vanderbilt 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model gives Vanderbilt an 85% chance of defeating Illinois.
According to our model, the 152.5-point over/under has a 54% chance of going over.
Illinois vs. Vanderbilt odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Illinois | Vanderbilt |
|---|---|---|
| Spread | +13.5 (-110) | -13.5 (-110) |
| Moneyline | +630 | -800 |
| Total | o152.5 (-110) | u152.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Illinois vs. Vanderbilt picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Illinois +13.5 | -110 |
| Moneyline | Illinois | +630 |
| Total | Over 152.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Over 152.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Illinois vs. Vanderbilt game-day updates and essential details
Monday's women's basketball game between Vanderbilt and Illinois at Memorial Gymnasium is scheduled to start at 7:00 PM ET.
- Who: Illinois vs. Vanderbilt
- Date: Monday, March 23, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Memorial Gymnasium
- March Madness stage: Second Round
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Conclusion
We predict Vanderbilt, with an 85% win probability, will likely beat Illinois this women's March Madness Second Round matchup.
AI and automation have enhanced this article to quickly deliver accurate Illinois vs. Vanderbilt insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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