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Illinois State vs. Northern Iowa prediction: Northern Iowa favored to win men's college basketball matchup [2/25/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Illinois State vs Northern Iowa predictions for college basketball Wednesday.
Northern Iowa will square off with Illinois State in men's college basketball action at McLeod Center on Wednesday, beginning at 7:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model predicts Northern Iowa as the most likely winner of the Illinois State vs. Northern Iowa game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Illinois State vs. Northern Iowa prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Illinois State and Northern Iowa 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Northern Iowa a 64% chance of beating Illinois State. Our predicted final score has Northern Iowa winning 68-64.
According to our model, Illinois State (+4.5) has a 55% chance of covering the spread, while the over/under total of 132.5 points has a 52% chance of going over.
Illinois State vs. Northern Iowa odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Illinois State | Northern Iowa |
|---|---|---|
| Spread | +4.5 (-102) | -4.5 (-118) |
| Moneyline | +198 | -225 |
| Total | o132.5 (-105) | u132.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Illinois State vs. Northern Iowa picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Illinois State +4.5 | -102 |
| Moneyline | Illinois State | +198 |
| Total | Over 132.5 | -105 |
According to our best men's college basketball bets, the top play to make on this game is Illinois State +4.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Illinois State vs. Northern Iowa game-day updates and essential details
Wednesday's men's college basketball game between Northern Iowa and Illinois State at McLeod Center is scheduled to commence at 7:00 PM ET.
- Who: Illinois State vs. Northern Iowa
- Date: Wednesday, February 25, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: McLeod Center
Conclusion
We predict Northern Iowa, with a 64% win probability, will likely beat Illinois State on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Illinois State vs. Northern Iowa insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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