Houston Texans vs. Los Angeles Chargers updated prediction featuring Nico Collins, Omarion Hampton [Week 17, 2025]

Dimers' latest NFL predictions are live for Los Angeles Chargers vs. Houston Texans in Week 17, with our model giving the Chargers a 57% of winning.

As Saturday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this AFC matchup.

Since our early Chargers-Texans predictions, we’ve updated the win probabilities, score projections, and TD odds for Nico Collins, Omarion Hampton, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Texans vs. Chargers page.

What's changed? Houston vs. LA Chargers updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Texans vs. Chargers matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Texans 43%, Chargers 57%
• Predicted Final Score: Texans 19-20 Chargers
• Spread: Texans (+1.5) 50%, Chargers (-1.5) 50%
• Total Points (39.5): Over 54%, Under 46%

As of December 25, 2025, these Texans-Chargers calculations reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 17 highlight the top candidates to find the end zone in Texans-Chargers on Saturday:

Houston Texans

• Nico Collins: 35.5% probability
• Woody Marks: 34.3% probability
• Dalton Schultz: 22.6% probability

Los Angeles Chargers

• Omarion Hampton: 44.0% probability
• Ladd McConkey: 30.0% probability
• Quentin Johnston: 28.0% probability

Texans vs. Chargers latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Texans +1.5 (-105), Chargers -1.5 (-115)
• Moneyline: Texans +110, Chargers -125
• Total: Over/Under 39.5 (-108/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Texans vs. Chargers Week 17 details

The NFL Week 17 matchup between the Chargers and Texans at SoFi Stadium is scheduled for December 27, 2025.

• Who: Houston Texans vs. Los Angeles Chargers
• Date: Saturday, December 27, 2025
• Time: 4:30 PM ET/1:30PM PT
• Venue: SoFi Stadium

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Conclusion

We predict the Chargers, with a 57% win probability, will likely beat the Texans in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Texans vs. Chargers game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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