Astros vs. Blue Jays prediction: Why Toronto is favored to win Wednesday's MLB matchup [6/24/2026]
Get Houston Astros vs Toronto Blue Jays predictions for MLB Wednesday.

The Toronto Blue Jays will square off with the Houston Astros in MLB action at Rogers Centre on Wednesday, starting at 7:07 PM ET.
Trey Yesavage (3-3, 3.76 ERA) will start for the Blue Jays, pitting him against Mike Burrows (3-8, 5.79 ERA) for the Astros.
Based on the latest simulations, Dimers' advanced MLB model predicts the Blue Jays as the most likely winner of the Astros vs. Blue Jays game.
This article offers further insights into Wednesday's matchup, including best bets and picks.
Astros vs. Blue Jays prediction: Who will win and cover?
Our independent predictive model gives the Blue Jays a 59.6% chance of defeating the Astros.
According to our model, the Astros (+1.5) have a 58.2% chance of covering the run line, while the 8.5-run over/under has a 52.6% chance of going over,.
Astros vs. Blue Jays odds [6/24/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Astros | Blue Jays |
|---|---|---|
| Run Line | +1.5 (-155) | -1.5 (+136) |
| Moneyline | +135 | -154 |
| Total | o8.5 (-105) | u8.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Astros vs. Blue Jays picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Blue Jays -1.5 | +136 |
| Moneyline | Blue Jays | -154 |
| Total | Over 8.5 | -105 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Blue Jays game-day updates and essential details
Wednesday's MLB matchup between the Blue Jays and Astros at Rogers Centre is scheduled to begin at 7:07 PM ET.
- Who: Houston Astros vs. Toronto Blue Jays
- Date: Wednesday, June 24, 2026
- Time: 7:07 PM ET/4:07PM PT
- Venue: Rogers Centre
Conclusion
We predict the Blue Jays, with a 59.6% win probability, will likely beat the Astros in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



