Harvard vs. Columbia prediction: Why Harvard is favored to win in college football Week 11, 2025

Columbia and Harvard will meet in Week 11 college football action at Robert K. Kraft Field at Lawrence A. Wien Stadium on Friday, starting at 7:00PM ET.

Based on the latest simulation results, Dimers' advanced college football model projects Harvard as the most likely winner of the Harvard vs. Columbia game.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Harvard vs. Columbia prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Harvard vs. Columbia 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Harvard a 98% chance of defeating Columbia. Our predicted final score has Harvard winning 38-10.

According to our model, Columbia (+29.5) has a 52% chance of covering the spread, while the over/under total of 48.5 points has an equal 50-50 chance of hitting.

Harvard vs. Columbia odds

We have researched the best College Football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Harvard vs. Columbia picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our college football best bets, the top play to make on this game is Harvard to win.

Harvard vs. Columbia game-day updates and essential details

Friday's college football action between Columbia and Harvard at Robert K. Kraft Field at Lawrence A. Wien Stadium is scheduled to begin at 7:00PM ET.

• Who: Harvard vs. Columbia
• Date: Friday, November 7, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Robert K. Kraft Field at Lawrence A. Wien Stadium

Conclusion

We predict Harvard, with a 98% win probability, will likely beat Columbia on Friday.

AI and automation have enhanced this article to quickly deliver accurate Harvard vs. Columbia insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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