Georgetown vs. DePaul prediction: DePaul favored to win men's college basketball matchup [3/11/2026]

DePaul will face Georgetown, in what is expected to be a close men's college basketball game, at Madison Square Garden on Wednesday, starting at 9:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model gives DePaul a slight edge with a 54% win probability over Georgetown.

This article offers a closer look at Wednesday's Georgetown vs. DePaul matchup, including an expanded look at the predicted score, best bets and picks.

Georgetown vs. DePaul prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Georgetown and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives DePaul a 54% chance of defeating Georgetown. Our predicted final score has DePaul winning 69-68.

According to our model, Georgetown (+1.5) has a 55% chance of covering the spread, while the over/under total of 136.5 points has a 54% chance of going over.

Georgetown vs. DePaul odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Georgetown	DePaul
Spread	+1.5 (-118)	-1.5 (+110)
Moneyline	+100	-118
Total	o136.5 (-105)	u136.5 (-110)

All odds are correct at the time of publication and are subject to change.

Georgetown vs. DePaul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Georgetown +1.5	-118
Moneyline	DePaul	-118
Total	Over 136.5	-105

According to our men's college basketball best bets, the top play to make on this game is Over 136.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Georgetown vs. DePaul game-day updates and essential details

Wednesday's men's college basketball game between DePaul and Georgetown at Madison Square Garden is scheduled to commence at 9:00 PM ET.

• Who: Georgetown vs. DePaul
• Date: Wednesday, March 11, 2026
• Time: 9:00 PM ET/6:00PM PT
• Venue: Madison Square Garden

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Conclusion

We predict DePaul, with a 54% win probability, will likely beat Georgetown on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Georgetown vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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