Oilers vs. Panthers prediction: Florida favored to win Saturday's NHL matchup [11/22/2025]

The Florida Panthers will take on the Edmonton Oilers in NHL action at Amerant Bank Arena on Saturday, beginning at 7:00PM ET.

Based on updated simulations, Dimers' advanced NHL model projects the Panthers as the most likely winner of the Oilers vs. Panthers game.

This article offers further insights into Saturday's matchup, including projected goal scorers, best bets and player prop picks.

Oilers vs. Panthers prediction: Who will win and cover?

As part of Dimers' NHL predictions coverage—and following a review of recent results—our pregame model has generated moneyline, puck line, and over/under probabilities for Saturday's clash between the Oilers and Panthers.

Our famous predictive model currently gives the Panthers a 56% chance of beating the Oilers.

According to our model, the Oilers (+1.5) have a 66% chance of covering the puck line, while the over/under total of six goals has an equal 50-50 chance of hitting.

Oilers vs. Panthers odds

We have researched the best NHL odds in America for this game, which are listed here:

Bet Type	Oilers	Panthers
Puck Line	+1.5 (-225)	-1.5 (+195)
Moneyline	+110	-130
Total	o6 (-110)	u6 (-110)

All odds are correct at the time of publication and are subject to change.

Oilers vs. Panthers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Puck Line	Panthers -1.5	+195
Moneyline	Panthers	-130
Total	Under 6	-110

According to our NHL best bets, the top play to make on this game is Panthers -1.5 at the spread.

Oilers vs. Panthers player props

Who will score a goal in Oilers vs. Panthers?

According to our model, Sam Reinhart is most likely to score an anytime goal in Oilers vs. Panthers.

Our projections give Reinhart a 43.0% chance of scoring a goal at Amerant Bank Arena, while the star is a 9.7% chance of netting the first goal the game.

Anytime goal scorer predictions

Edmonton Oilers

Player	Anytime Goal Probability
Leon Draisaitl	43.0%
Zach Hyman	34.4%
Connor McDavid	32.8%
Jack Roslovic	23.7%
Andrew Mangiapane	17.2%

Florida Panthers

Player	Anytime Goal Probability
Sam Reinhart	43.0%
Brad Marchand	37.8%
Sam Bennett	27.0%
Carter Verhaeghe	24.3%
Evan Rodrigues	23.3%

First goal scorer predictions

Edmonton Oilers

Player	First Goal Probability
Leon Draisaitl	9.3%
Zach Hyman	7.1%
Connor McDavid	6.3%
Jack Roslovic	4.8%
Andrew Mangiapane	3.1%

Florida Panthers

Player	First Goal Probability
Sam Reinhart	9.7%
Brad Marchand	7.4%
Sam Bennett	4.7%
Evan Rodrigues	4.5%
Carter Verhaeghe	4.3%

Oilers vs. Panthers game-day updates and essential details

Saturday's matchup between the Panthers and Oilers at Amerant Bank Arena is scheduled to begin at 7:00PM ET.

• Who: Edmonton Oilers vs. Florida Panthers
• Date: Saturday, November 22, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Amerant Bank Arena

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Conclusion

We predict the Panthers, with a 56% win probability, will likely beat the Oilers on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Oilers vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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