Duke vs. Virginia prediction: Virginia favored to win ACC Championship, 2025

Virginia and Duke will lock horns in the 2025 ACC Championship Game at Bank of America Stadium on Saturday, beginning at 8:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts Virginia as the most likely winner of the Duke vs. Virginia game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

ACC Championship Game prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Duke vs. Virginia 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Virginia a 60% chance of defeating Duke. Our predicted final score has Virginia winning 29-25.

According to our model, Virginia (-4) has a 51% chance of covering the spread, while the over/under total of 57.5 points has a 53% chance of going over.

Duke vs. Virginia odds

We have sourced the best college football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Duke vs. Virginia picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: