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Pistons vs. Spurs prediction: San Antonio favored to win Thursday's NBA game [3/5/2026]
Get Detroit Pistons vs San Antonio Spurs predictions for NBA Thursday.

The San Antonio Spurs will square off with the Detroit Pistons in NBA action at Frost Bank Center on Thursday, starting at 8:00 PM ET.
Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Pistons vs. Spurs game.
This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like Victor Wembanyama, De'Aaron Fox and Stephon Castle, while the Pistons will be led by Cade Cunningham, Jalen Duren and Tobias Harris.
This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pistons vs. Spurs prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Thursday's NBA game between the Pistons and Spurs 10,000 times as part of our NBA predictions coverage.
Our leading predictive model gives the Spurs a 61% chance of defeating the Pistons. Our predicted final score has the Spurs winning 115-112.
According to our model, the Spurs (-3.5) have a 51% chance of covering the spread, while the 228.5-point over/under has an equal 50-50 chance of hitting.
Pistons vs. Spurs odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Pistons | Spurs |
|---|---|---|
| Spread | +3.5 (-125) | -3.5 (-105) |
| Moneyline | +130 | -148 |
| Total | o228.5 (-106) | u228.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Pistons vs. Spurs picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Spurs -3.5 | -105 |
| Moneyline | Spurs | -148 |
| Total | Over 228.5 | -106 |
According to our best NBA bets for Thursday, the top play to make on this game is Spurs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Pistons vs. Spurs player props
NBA prop bets are a great way to wager on Thursday's Detroit vs. San Antonio matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Frost Bank Center.
Cade Cunningham is expected to lead the Pistons with 26 points, 6 rebounds and 9 assists, while Victor Wembanyama is projected to have 25 points, 11 rebounds and 3 assists for the Spurs.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Pistons prediction
Our model's projected player stats for the Pistons are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Cade Cunningham | 26 | 6 | 9 | 2 | 55 |
| Jalen Duren | 19 | 11 | 2 | 0 | 40 |
| Tobias Harris | 14 | 5 | 2 | 1 | 28 |
| Duncan Robinson | 13 | 3 | 2 | 3 | 23 |
| Ausar Thompson | 10 | 6 | 3 | 0 | 28 |
Spurs prediction
Projected points, rebounds, assists and three-pointers made for the Spurs:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| V. Wembanyama | 25 | 11 | 3 | 2 | 56 |
| De'Aaron Fox | 17 | 3 | 6 | 2 | 35 |
| Stephon Castle | 16 | 5 | 6 | 1 | 37 |
| Devin Vassell | 14 | 4 | 2 | 2 | 27 |
| Keldon Johnson | 13 | 5 | 1 | 1 | 24 |
Pistons vs. Spurs game-day updates and essential details
Thursday's action between the Spurs and Pistons at Frost Bank Center is scheduled to begin at 8:00 PM ET.
- Who: Detroit Pistons vs. San Antonio Spurs
- Date: Thursday, March 5, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Frost Bank Center
Conclusion
We predict the Spurs, with a 61% win probability, will likely beat the Pistons on Thursday, with Victor Wembanyama projected for a game-high 56 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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