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Pistons vs. Spurs prediction: San Antonio favored to win Thursday's NBA game [3/5/2026]

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Written by Jason Bevilacqua

Get Detroit Pistons vs San Antonio Spurs predictions for NBA Thursday.

Detroit Pistons-San Antonio Spurs Predictions and Game Preview.
Detroit Pistons vs. San Antonio Spurs NBA prediction for Thursday, March 5, 2026.

The San Antonio Spurs will square off with the Detroit Pistons in NBA action at Frost Bank Center on Thursday, starting at 8:00 PM ET.

Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Pistons vs. Spurs game.

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like Victor Wembanyama, De'Aaron Fox and Stephon Castle, while the Pistons will be led by Cade Cunningham, Jalen Duren and Tobias Harris.

This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pistons vs. Spurs prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Thursday's NBA game between the Pistons and Spurs 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Spurs a 61% chance of defeating the Pistons. Our predicted final score has the Spurs winning 115-112.

According to our model, the Spurs (-3.5) have a 51% chance of covering the spread, while the 228.5-point over/under has an equal 50-50 chance of hitting.

 

Pistons vs. Spurs odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Pistons Spurs
Spread +3.5 (-125) -3.5 (-105)
Moneyline +130 -148
Total o228.5 (-106) u228.5 (-110)

All odds are correct at the time of publication and are subject to change.

Pistons vs. Spurs picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Spurs -3.5 -105
Moneyline Spurs -148
Total Over 228.5 -106

According to our best NBA bets for Thursday, the top play to make on this game is Spurs to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Pistons vs. Spurs player props

NBA prop bets are a great way to wager on Thursday's Detroit vs. San Antonio matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Frost Bank Center.

Cade Cunningham is expected to lead the Pistons with 26 points, 6 rebounds and 9 assists, while Victor Wembanyama is projected to have 25 points, 11 rebounds and 3 assists for the Spurs.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Pistons prediction

Our model's projected player stats for the Pistons are:

Player PTS REB AST 3PM DFS
Cade Cunningham 26 6 9 2 55
Jalen Duren 19 11 2 0 40
Tobias Harris 14 5 2 1 28
Duncan Robinson 13 3 2 3 23
Ausar Thompson 10 6 3 0 28

Spurs prediction

Projected points, rebounds, assists and three-pointers made for the Spurs:

Player PTS REB AST 3PM DFS
V. Wembanyama 25 11 3 2 56
De'Aaron Fox 17 3 6 2 35
Stephon Castle 16 5 6 1 37
Devin Vassell 14 4 2 2 27
Keldon Johnson 13 5 1 1 24

Pistons vs. Spurs game-day updates and essential details

Thursday's action between the Spurs and Pistons at Frost Bank Center is scheduled to begin at 8:00 PM ET.

Conclusion

We predict the Spurs, with a 61% win probability, will likely beat the Pistons on Thursday, with Victor Wembanyama projected for a game-high 56 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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