Detroit Lions vs. Minnesota Vikings: Experts release early Week 17 projections [2025]

The Detroit Lions and Minnesota Vikings will meet in Week 17 of the NFL season at U.S. Bank Stadium on Thursday, December 25, 2025, starting at 4:30 PM ET.

Initial simulations from Dimers' trusted NFL model favor the Lions as the most likely winner of this NFC North rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Lions vs. Vikings predictions page.

Detroit vs. Minnesota early predictions

Leveraging trusted machine learning and analysis, we have simulated the Lions vs. Vikings game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Lions 63%, Vikings 37%
• Predicted final score: Lions 25-22 Vikings
• Spread: Lions (-2.5) 59%, Vikings (+2.5) 41%
• Total points (48.5): Over 45%, Under 55%

As of December 22, 2025, these Lions-Vikings figures and predictions reflect the latest data and insights available.

Lions vs. Vikings Week 17 details

The NFL Week 17 game between the Vikings and Lions at U.S. Bank Stadium is scheduled for December 25, 2025.

• Who: Detroit Lions vs. Minnesota Vikings
• Date: Thursday, December 25, 2025
• Time: 4:30 PM ET/1:30PM PT
• Venue: U.S. Bank Stadium

Lions vs. Vikings opening odds

We've researched the best betting odds across America for this Week 17 game, which are listed here:

• Spread: Lions -2.5 (-110), Vikings +2.5 (-110)
• Moneyline: Lions -130, Vikings +176
• Total: Over/Under 48.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Lions, with a 63% win probability, will likely beat the Vikings in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Lions vs. Vikings game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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