Creighton vs. Seton Hall prediction: Seton Hall favored to win men's college basketball matchup [3/12/2026]

Seton Hall and Creighton will meet in men's college basketball action at Madison Square Garden on Thursday, with tipoff at 2:30 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Seton Hall as the most likely winner of the Creighton vs. Seton Hall game.

This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Creighton vs. Seton Hall prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Thursday's NCAA basketball matchup between Creighton and Seton Hall 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Seton Hall a 61% chance of defeating Creighton. Our predicted final score has Seton Hall winning 68-66.

According to our model, Creighton (+3.5) has a 54% chance of covering the spread, while the 135.5-point over/under has a 51% chance of staying under.

Creighton vs. Seton Hall odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Creighton	Seton Hall
Spread	+3.5 (-115)	-3.5 (-105)
Moneyline	+136	-162
Total	o135.5 (-115)	u135.5 (-105)

All odds are correct at the time of publication and are subject to change.

Creighton vs. Seton Hall picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Creighton +3.5	-115
Moneyline	Seton Hall	-162
Total	Under 135.5	-105

According to our men's college basketball best bets, the top play to make on this game is Creighton +3.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Creighton vs. Seton Hall game-day updates and essential details

Thursday's men's college basketball game between Seton Hall and Creighton at Madison Square Garden is scheduled to start at 2:30 PM ET.

• Who: Creighton vs. Seton Hall
• Date: Thursday, March 12, 2026
• Time: 2:30 PM ET/11:30AM PT
• Venue: Madison Square Garden

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Conclusion

We predict Seton Hall, with a 61% win probability, will likely beat Creighton on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Creighton vs. Seton Hall insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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