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UConn vs. DePaul prediction: Connecticut favored to win women's college basketball matchup [2/4/2026]
Get UConn vs DePaul predictions for college basketball Wednesday.

Women's college basketball action continues on Wednesday at 8:00 PM ET as UConn locks horns with DePaul at Wintrust Arena.
Based on the latest simulation results, Dimers' new women's basketball model predicts Connecticut as the most likely winner of the UConn vs. DePaul game.
This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.
UConn vs. DePaul prediction: Who will win?
Using powerful machine learning and data analysis, we have simulated the outcome of Wednesday's women's basketball matchup between UConn and DePaul 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model currently gives Connecticut a 99% chance of beating DePaul.
According to our model, the over/under total of 145.5 points has a 51% chance of going over.
UConn vs. DePaul odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | UConn | DePaul |
|---|---|---|
| Spread | -54.5 (-110) | +54.5 (-110) |
| Total | o145.5 (-108) | u145.5 (-110) |
All odds are correct at the time of publication and are subject to change.
UConn vs. DePaul picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul +54.5 | -110 |
| Total | Over 145.5 | -108 |
According to our women's college basketball best bets, the top play to make on this game is DePaul +54.5.
UConn vs. DePaul game-day updates and essential details
Wednesday's women's basketball action between DePaul and UConn at Wintrust Arena is scheduled to start at 8:00 PM ET.
- Who: Connecticut vs. DePaul
- Date: Wednesday, February 4, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Wintrust Arena
Conclusion
We predict Connecticut, with a 99% win probability, will likely beat DePaul on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Connecticut vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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