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Browns vs. Steelers prediction: Why Pittsburgh is favored to win in NFL Week 6, 2025

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Written by Ryan Leaver

Get Cleveland Browns vs Pittsburgh Steelers predictions for NFL Sunday.

Cleveland Browns-Pittsburgh Steelers Predictions and Game Preview.
Cleveland Browns vs. Pittsburgh Steelers NFL prediction for Sunday, October 12, 2025.

The Pittsburgh Steelers will take on the Cleveland Browns in NFL Week 6 action at Acrisure Stadium on Sunday, beginning at 1:00PM ET.

Based on updated simulations, Dimers' advanced NFL model predicts the Steelers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Browns-Steelers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Steelers with a win probability of 75%, while the Browns have 25%."

This gameday Browns vs. Steelers betting preview builds on my Browns vs. Steelers prediction that was released earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Browns vs. Steelers predictions page.

Browns vs. Steelers predictions

Since our Browns-Steelers predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Browns and Steelers 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Steelers a 75% chance of defeating the Browns in Week 6 of the NFL season. Our predicted final score has the Steelers winning 22-16.

According to our model, the Steelers (-6) have a 54% chance of covering the spread, while the 37.5-point over/under has a 53% chance of going over.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 6 straight up picks.

Browns vs. Steelers odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Browns Steelers
Spread +6 (-110) -6 (-110)
Moneyline +240 -290
Total o37.5 (-115) u37.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Browns vs. Steelers picks and best bets

Our model's biggest edge in today's Browns vs. Steelers matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Browns vs. Steelers TD scorers

Who will score an anytime touchdown in Browns vs. Steelers?

According to our list of touchdown scorer predictions for Week 6, Cleveland's Quinshon Judkins is most likely to score the first touchdown in Browns vs. Steelers.

Our projections give Judkins a 12.8% chance of scoring the first TD at Acrisure Stadium, while the Browns running back is a 45.6% chance of reaching the end zone at any point in the game.

First touchdown scorer predictions

Cleveland Browns

Player First TD Probability
Quinshon Judkins (RB) 12.8%
David Njoku (TE) 4.6%
Jerry Jeudy (WR) 4.5%

Pittsburgh Steelers

Player First TD Probability
Jaylen Warren (RB) 11.2%
DK Metcalf (WR) 9.6%
Kenneth Gainwell (RB) 8.7%

Anytime touchdown scorer predictions

Cleveland Browns

Player Anytime TD Probability
Quinshon Judkins (RB) 45.6%
David Njoku (TE) 19.5%
Jerry Jeudy (WR) 19.4%

Pittsburgh Steelers

Player Anytime TD Probability
Jaylen Warren (RB) 38.9%
DK Metcalf (WR) 34.4%
Kenneth Gainwell (RB) 31.8%

Browns vs Steelers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Browns and Steelers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our NFL player projections page now to access player prop projections for every offensive player in this matchup and all other Week 6 games.

Browns vs. Steelers quarterbacks

Of the starting quarterbacks, the Browns' Dillon Gabriel is projected to throw for fewer yards than the Steelers' Aaron Rodgers.

Browns rushing

Quinshon Judkins, Dillon Gabriel and Jerome Ford are projected to be the leading rushers for the Browns.

Player Position
Quinshon Judkins RB
Dillon Gabriel QB
Jerome Ford RB

Steelers rushing

Jaylen Warren, Kenneth Gainwell and Kaleb Johnson are expected to lead the Steelers in rushing yards.

Player Position
Jaylen Warren RB
Kenneth Gainwell RB
Kaleb Johnson RB

Browns receiving

Jerry Jeudy, David Njoku, Isaiah Bond, Harold Fannin and Quinshon Judkins are projected to top the receiving yards for the Browns.

Player Position
Jerry Jeudy WR
David Njoku TE
Isaiah Bond WR
Harold Fannin TE
Quinshon Judkins RB

Steelers receiving

DK Metcalf, Jonnu Smith, Jaylen Warren, Pat Freiermuth and Roman Wilson are projected to lead the Steelers in receiving yards.

Player Position
DK Metcalf WR
Jonnu Smith TE
Jaylen Warren RB
Pat Freiermuth TE
Roman Wilson WR

Browns vs. Steelers game-day updates and essential details

The NFL Week 6 matchup between the Steelers and Browns at Acrisure Stadium is scheduled to start at 1:00PM ET.

Dimers' in-depth preview of Sunday's Browns vs. Steelers matchup includes our prediction, picks and the latest betting odds.

Before making any Browns vs. Steelers picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Steelers, with a 75% win probability, will likely beat the Browns in Week 6 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Browns vs. Steelers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Stay up-to-date with the latest NFL news and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the latest projections for the Super Bowl, AFC, NFC and each division.

Boost your NFL betting by exploring the latest NFL betting promos, sourced from top sportsbooks and DFS operators.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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