Reds vs. Guardians Prediction: Cleveland Predicted to Win Monday's MLB Matchup [6/9/2025]

The Cleveland Guardians and Cincinnati Reds are scheduled to meet in MLB action at Progressive Field on Monday, starting at 6:40PM ET.

Luis L. Ortiz (3-6, 4.02 ERA) will be on the bump for the Guardians, while the Reds will counter with Wade Miley (0-0, 18.00 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Guardians as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Cincinnati-Cleveland game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Guardians are likely to win, with a probability of 59%, compared to the Reds' 41%."

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Reds vs. Guardians predictions page.

Guardians vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Monday's MLB game between the Reds and Guardians 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Guardians a 59% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 60% chance of covering the run line, while the over/under total of 9 runs has a 53% chance of staying under.

Reds vs. Guardians Odds [6/9/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Guardians
Run Line	+1.5 (-154)	-1.5 (+135)
Moneyline	+135	-158
Total	o9 (-102)	u9 (-112)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Guardians Picks and Best Bets

Our model's strongest edge in today's Reds vs. Guardians matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Reds vs. Guardians Game-Day Updates and Essential Details

Monday's MLB game between the Guardians and Reds at Progressive Field is scheduled to start at 6:40PM ET.

• Who: Cincinnati Reds vs. Cleveland Guardians
• Date: Monday, June 9, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field

Dimers.com's full preview of Monday's Reds vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Cleveland picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Guardians, with a 59% win probability, will likely beat the Reds on Monday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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