White Sox vs. Astros Prediction: Houston Predicted to Win Tuesday's MLB Matchup [6/10/2025]

The Houston Astros and Chicago whitesox will meet in MLB action at Daikin Park on Tuesday, starting at 8:10PM ET.

Lance McCullers (1-1, 4.44 ERA) will get the ball for the Astros, up against Shane Smith (2-3, 2.46 ERA) for the White Sox.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's CHI White Sox-Houston game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Astros with a win probability of 63%, compared to 37% for the White Sox."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive White Sox vs. Astros predictions page.

Astros vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB matchup between the White Sox and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Astros a 63% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 56% chance of covering the run line, while the 7.5-run over/under has a 52% chance of staying under.

White Sox vs. Astros Odds [6/10/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Astros
Run Line	+1.5 (-144)	-1.5 (+125)
Moneyline	+148	-174
Total	o7.5 (-112)	u7.5 (-106)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Astros Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Astros matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

White Sox vs. Astros Game-Day Updates and Essential Details

Tuesday's MLB game between the Astros and White Sox at Daikin Park is scheduled to start at 8:10PM ET.

• Who: Chicago White Sox vs. Houston Astros
• Date: Tuesday, June 10, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's in-depth preview of Tuesday's White Sox vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
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Conclusion

We predict the Astros, with a 63% win probability, will likely beat the White Sox on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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