Charleston Southern vs. Winthrop prediction: Why Winthrop is favored to win men's college basketball matchup [3/6/2026]

Winthrop will face Charleston Southern in men's college basketball action at Freedom Hall Civic Center on Friday, commencing at 2:30 PM ET.

Based on updated simulations, Dimers' proven college basketball model projects Winthrop as the most likely winner of the Charleston Southern vs. Winthrop game.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Charleston Southern vs. Winthrop prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Friday's NCAA basketball game between Charleston Southern and Winthrop 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Winthrop a 72% chance of defeating Charleston Southern. Our predicted final score has Winthrop winning 84-77.

According to our model, the bookmakers have got it right, and Charleston Southern and Winthrop each have a 50% chance of covering the spread, while the 164.5-point over/under has a 53% chance of staying under.

Charleston Southern vs. Winthrop odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Charleston Southern	Winthrop
Spread	+6.5 (-105)	-6.5 (-110)
Moneyline	+230	-245
Total	o164.5 (-110)	u164.5 (-110)

All odds are correct at the time of publication and are subject to change.

Charleston Southern vs. Winthrop picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Charleston Southern +6.5	-105
Moneyline	Winthrop	-245
Total	Under 164.5	-110

According to our men's college basketball best bets, the top play to make on this game is Winthrop to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Charleston Southern vs. Winthrop game-day updates and essential details

Friday's men's college basketball action between Winthrop and Charleston Southern at Freedom Hall Civic Center is scheduled to begin at 2:30 PM ET.

• Who: Charleston Southern vs. Winthrop
• Date: Friday, March 6, 2026
• Time: 2:30 PM ET/11:30AM PT
• Venue: Freedom Hall Civic Center

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Conclusion

We predict Winthrop, with a 72% win probability, will likely beat Charleston Southern on Friday.

AI and automation have enhanced this article to quickly deliver accurate Charleston Southern vs. Winthrop insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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