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Flames vs. Sabres prediction: Buffalo favored to win Wednesday's NHL matchup [11/19/2025]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get Calgary Flames vs Buffalo Sabres predictions for NHL Wednesday.
NHL action continues on Wednesday at 7:30PM ET as the Calgary Flames lock horns with the Buffalo Sabres at KeyBank Center.
Based on the latest simulations, Dimers' proven NHL model predicts the Sabres as the most likely winner of the Flames vs. Sabres game.
This article offers a closer look at Wednesday's matchup, including projected goal scorers, best bets and player prop picks.
Flames vs. Sabres prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Wednesday's NHL matchup between the Flames and Sabres 10,000 times as part of our NHL predictions coverage.
Our leading predictive model currently gives the Sabres a 56% chance of defeating the Flames.
According to our model, the Flames (+1.5) have a 65% chance of covering the puck line, while the 6-goal over/under has a 52% chance of staying under.
Flames vs. Sabres odds
We have researched the best NHL odds in America for this game, which are listed here:
| Bet Type | Flames | Sabres |
|---|---|---|
| Puck Line | +1.5 (-190) | -1.5 (+160) |
| Moneyline | +132 | -155 |
| Total | o6 (-115) | u6 (-105) |
All odds are correct at the time of publication and are subject to change.
Flames vs. Sabres picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Puck Line | Flames +1.5 | -190 |
| Moneyline | Flames | +132 |
| Total | Under 6 | -105 |
According to our NHL best bets, the top play to make on this game is Flames to win.
Flames vs. Sabres player props
Who will score a goal in Flames vs. Sabres?
According to our model, Tage Thompson is most likely to score an anytime goal in Flames vs. Sabres.
Our projections give Thompson a 44.4% chance of scoring a goal at KeyBank Center, while the star is a 9.2% chance of netting the first goal the game.
Anytime goal scorer predictions
Calgary Flames
| Player | Anytime Goal Probability |
|---|---|
| Nazem Kadri | 32.9% |
| Matthew Coronato | 30.5% |
| Jonathan Huberdeau | 28.0% |
| Yegor Sharangovich | 21.4% |
| Morgan Frost | 21.4% |
Buffalo Sabres
| Player | Anytime Goal Probability |
|---|---|
| Tage Thompson | 44.4% |
| Alex Tuch | 33.3% |
| Jack Quinn | 23.8% |
| Ryan McLeod | 23.2% |
| Noah Ostlund | 20.2% |
First goal scorer predictions
Calgary Flames
| Player | First Goal Probability |
|---|---|
| Nazem Kadri | 6.2% |
| Matthew Coronato | 5.9% |
| Jonathan Huberdeau | 5.5% |
| Yegor Sharangovich | 3.8% |
| Blake Coleman | 3.8% |
Buffalo Sabres
| Player | First Goal Probability |
|---|---|
| Tage Thompson | 9.2% |
| Alex Tuch | 6.8% |
| Jack Quinn | 4.6% |
| Ryan McLeod | 4.0% |
| Noah Ostlund | 3.6% |
Flames vs. Sabres game-day updates and essential details
Wednesday's matchup between the Sabres and Flames at KeyBank Center is scheduled to commence at 7:30PM ET.
- Who: Calgary Flames vs. Buffalo Sabres
- Date: Wednesday, November 19, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: KeyBank Center
Conclusion
We predict the Sabres, with a 56% win probability, will likely beat the Flames on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Flames vs. Sabres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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