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Butler vs. DePaul prediction: Butler favored to win NCAAW matchup [2/25/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Butler vs DePaul predictions for college basketball Wednesday.
DePaul will square off with Butler, in what is expected to be a tight women's college basketball game, at Wintrust Arena on Wednesday, starting at 7:00 PM ET.
Based on the latest simulations, Dimers' new women's basketball model gives Butler a slight edge with a 53% win probability over DePaul.
This article offers further insights into Wednesday's Butler vs. DePaul matchup, including best bets and picks.
Butler vs. DePaul prediction: Who will win?
Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's women's basketball matchup between Butler and DePaul 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model gives Butler a 53% chance of beating DePaul.
According to our model, the 133.5-point over/under has an equal 50-50 chance of hitting.
Butler vs. DePaul odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Butler | DePaul |
|---|---|---|
| Spread | -1.5 (-120) | +1.5 (+100) |
| Moneyline | -142 | +120 |
| Total | o133.5 (-110) | u133.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Butler vs. DePaul picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul +1.5 | +100 |
| Moneyline | DePaul | +120 |
| Total | Under 133.5 | -110 |
According to our best women's college basketball bets, the top play to make on this game is DePaul to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Butler vs. DePaul game-day updates and essential details
Wednesday's women's basketball action between DePaul and Butler at Wintrust Arena is scheduled to start at 7:00 PM ET.
- Who: Butler vs. DePaul
- Date: Wednesday, February 25, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Wintrust Arena
Conclusion
We predict Butler, with a 53% win probability, will likely beat DePaul on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Butler vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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