Butler vs. DePaul prediction: DePaul favored to win men's college basketball matchup [3/7/2026]

DePaul will take on Butler in men's college basketball action at Wintrust Arena on Saturday, commencing at 12:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts DePaul as the most likely winner of the Butler vs. DePaul game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Butler vs. DePaul prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball game between Butler and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives DePaul a 63% chance of defeating Butler. Our predicted final score has DePaul winning 73-70.

According to our model, Butler (+3.5) has a 51% chance of covering the spread, while the 142.5-point over/under has a 51% chance of staying under.

Butler vs. DePaul odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Butler	DePaul
Spread	+3.5 (-104)	-3.5 (-115)
Moneyline	+150	-180
Total	o142.5 (-110)	u142.5 (-108)

All odds are correct at the time of publication and are subject to change.

Butler vs. DePaul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Butler +3.5	-104
Moneyline	DePaul	-180
Total	Under 142.5	-108

According to our men's college basketball best bets, the top play to make on this game is Butler +3.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Butler vs. DePaul game-day updates and essential details

Saturday's men's college basketball action between DePaul and Butler at Wintrust Arena is scheduled to commence at 12:00 PM ET.

• Who: Butler vs. DePaul
• Date: Saturday, March 7, 2026
• Time: 12:00 PM ET/9:00AM PT
• Venue: Wintrust Arena

College basketball betting promos and codes

Make the most of Dimers' Butler vs. DePaul predictions by exploring the below offers from Bet365 and BetMGM.

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $150 in bonus bets win or lose with code "DIMERS".

BetMGM

Sign up to BetMGM with code "DIMERS" now to unlock their 'Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win' offer.

Conclusion

We predict DePaul, with a 63% win probability, will likely beat Butler on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Butler vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.