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Red Sox vs. Giants Prediction: San Francisco Predicted to Win Friday's MLB Matchup [6/20/2025]

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Written by Dave Garofolo

Our expert prediction for Friday's Boston Red Sox vs San Francisco Giants matchup.

Boston Red Sox-San Francisco Giants Predictions and Game Preview.
Oracle Park sets the stage for the MLB matchup between the Boston Red Sox and San Francisco Giants this Friday.

The San Francisco Giants will take on the Boston Red Sox in MLB action at Oracle Park on Friday, commencing at 10:15PM ET.

Hayden Birdsong (3-1, 2.79 ERA) will be the starting pitcher for the Giants, while the Red Sox are going with Hunter Dobbins (4-1, 3.74 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Giants as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Red Sox-Giants game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Giants' chance of winning is 56%, while the Red Sox' is 44%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Red Sox vs. Giants predictions page.

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Giants vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Friday's MLB game between the Red Sox and Giants 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Giants a 56% chance of beating the Red Sox.

According to our model, the Red Sox (+1.5) have a 63% chance of covering the run line, while the 7-run over/under has a 52% chance of going over.

Pre-Game Probabilities
Last Updated: 2:28AM, Jun 21
Moneyline
Over / Under
Run Line
Red Sox
Win %
41%
59%
Get the best bets with Dimers Pro
See Matchup
Giants
Red Sox BOS
Win %
41%
59%
See Matchup
Giants SF
Hunter Dobbins 4-1, 3.74 ERA
Hayden Birdsong 3-1, 2.79 ERA
Get the best bets with Dimers Pro

Red Sox vs. Giants Odds [6/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Red Sox Giants
Run Line +1.5 (-200) -1.5 (+170)
Moneyline +112 -130
Total o7 (-124) u7 (+105)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Giants Picks and Best Bets

Our model's strongest edge in today's Red Sox vs. Giants matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Red Sox vs. Giants Game-Day Updates and Essential Details

Friday's MLB action between the Giants and Red Sox at Oracle Park is scheduled to commence at 10:15PM ET.

Dimers.com's in-depth preview of Friday's Red Sox vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Giants picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Giants, with a 56% win probability, will likely beat the Red Sox on Friday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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