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Baylor vs. Duke prediction: Duke favored to win women's March Madness Second Round matchup [3/22/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Baylor vs Duke predictions for college basketball Sunday.
Duke will square off with Baylor in March Madness Second Round action at Cameron Indoor Stadium on Sunday, starting at 4:00 PM ET.
Based on updated simulation results, Dimers' new women's basketball model projects Duke as the most likely winner of the Baylor vs. Duke game.
This article offers an expanded analysis of Sunday's matchup, including best bets and picks.
Baylor vs. Duke prediction: Who will win and advance to the Sweet Sixteen?
Using innovative machine learning and data analysis, we have simulated the result of Sunday's NCAAW Tournament matchup between Baylor and Duke 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model currently gives Duke an 87% chance of defeating Baylor.
According to our model, the 126.5-point over/under has a 52% chance of going over.
Baylor vs. Duke odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Baylor | Duke |
|---|---|---|
| Spread | +12.5 (-106) | -12.5 (-110) |
| Moneyline | +680 | -1000 |
| Total | o126.5 (-110) | u126.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Baylor vs. Duke picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke -12.5 | -110 |
| Moneyline | Baylor | +680 |
| Total | Over 126.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Baylor to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Baylor vs. Duke game-day updates and essential details
Sunday's women's basketball game between Duke and Baylor at Cameron Indoor Stadium is scheduled to commence at 4:00 PM ET.
- Who: Baylor vs. Duke
- Date: Sunday, March 22, 2026
- Time: 4:00 PM ET/1:00PM PT
- Venue: Cameron Indoor Stadium
- March Madness stage: Second Round
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Conclusion
We predict Duke, with an 87% win probability, will likely beat Baylor this women's March Madness Second Round matchup.
AI and automation have enhanced this article to quickly deliver accurate Baylor vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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