...
...
Read Article
- More Betting
American University vs. Lafayette prediction: American University favored to win men's college basketball matchup [2/22/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get American University vs Lafayette predictions for college basketball Sunday.
Lafayette will face American University in men's college basketball action at Kirby Sports Center on Sunday, starting at 12:00 PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts American University as the most likely winner of the American University vs. Lafayette game.
This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
American University vs. Lafayette prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between American University and Lafayette 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives American University a 69% chance of defeating Lafayette. Our predicted final score has American University winning 73-68.
According to our model, American University (-3.5) has a 51% chance of covering the spread, while the over/under total of 141.5 points has an equal 50-50 chance of hitting.
American University vs. Lafayette odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | American University | Lafayette |
|---|---|---|
| Spread | -3.5 (-105) | +3.5 (-110) |
| Moneyline | -170 | +154 |
| Total | o141.5 (-108) | u141.5 (-105) |
All odds are correct at the time of publication and are subject to change.
American University vs. Lafayette picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | American University -3.5 | -105 |
| Moneyline | American University | -170 |
| Total | Under 141.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is American University to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
American University vs. Lafayette game-day updates and essential details
Sunday's men's college basketball game between Lafayette and American University at Kirby Sports Center is scheduled to start at 12:00 PM ET.
- Who: American University vs. Lafayette
- Date: Sunday, February 22, 2026
- Time: 12:00 PM ET/9:00AM PT
- Venue: Kirby Sports Center
Conclusion
We predict American University, with a 69% win probability, will likely beat Lafayette on Sunday.
AI and automation have enhanced this article to quickly deliver accurate American University vs. Lafayette insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
Advertiser disclosure