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Alabama vs. Oklahoma prediction: Oklahoma favored to win in college football playoffs first round [2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Alabama vs Oklahoma predictions for college football Friday.
Oklahoma and Alabama will lock horns in Week 17 college football playoffs action at Gaylord Family Oklahoma Memorial Stadium on Friday, with kickoff at 8:00 PM ET.
Based on updated simulation results, Dimers' advanced college football model predicts Oklahoma as the most likely winner of the Alabama vs. Oklahoma game.
This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.
Alabama vs. Oklahoma prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Alabama vs. Oklahoma 10,000 times as part of our college football predictions coverage.
Our famous predictive model gives Oklahoma a 56% chance of beating Alabama and advancing to play Indiana in the Rose Bowl Bowl. Our predicted final score has Oklahoma winning 22-21.
According to our model, the bookmakers have got it right, and Alabama and Oklahoma each have a 50% chance of covering the spread, while the 40.5-point over/under has a 55% chance of staying under.
Alabama vs. Oklahoma odds
We have researched the best college football odds in America for this game, which are listed here:
| Bet Type | Alabama | Oklahoma |
|---|---|---|
| Spread | +1.5 (-112) | -1.5 (-105) |
| Moneyline | -104 | -112 |
| Total | o40.5 (-110) | u40.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Alabama vs. Oklahoma picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Oklahoma -1.5 | -105 |
| Moneyline | Oklahoma | -112 |
| Total | Under 40.5 | -105 |
According to our college football best bets, the top play to make on this game is Under 40.5 total points.
Alabama vs. Oklahoma game-day updates and essential details
Friday's college football action between Oklahoma and Alabama at Gaylord Family Oklahoma Memorial Stadium is scheduled to commence at 8:00 PM ET.
- Who: Alabama vs. Oklahoma
- Date: Friday, December 19, 2025
- Time: 8:00 PM ET/5:00PM PT
- Venue: Gaylord Family Oklahoma Memorial Stadium
- Playoffs Stage: First Round
The 2025–26 season marks the second year of the expanded 12-team College Football Playoff, which replaced the long-standing four-team system last year..
Under the updated format, the four highest-ranked conference champions earn first-round byes, while seeds 5 through 12 meet in campus-site first-round games on December 20 and 21.
The winner of the Alabama vs. Oklahoma matchup will advance to face Indiana in the Rose Bowl.
Conclusion
We predict Oklahoma, with a 56% win probability, will likely beat Alabama in the first round of the College Football Playoff.
AI and automation have enhanced this article to quickly deliver accurate Alabama vs. Oklahoma insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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