D-Backs vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the D-Backs vs. Cardinals MLB game on June 22, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
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MLB sport icon
MLB
D-Backs
Merrill Kelly 5-6, 5.81 ERA
2
3
Busch Stadium
Cardinals
Andre Pallante 8-4, 3.76 ERA
Busch Stadium
1 2 3 4 5 6 7 8 9 RHE
D-Backs
0 0 0 0 0 1 1 0 0 2 8 0
Cardinals
0 0 1 2 0 0 0 0 X 3 7 0
Live Probabilities
Win %
  • D-Backs
    0%
  • Cardinals
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Tommy Troy pops out to Ivan Herrera.
Quick Box Score
D-Backs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 K. Marte 2B4020000.5001.000
2 G. Perdomo SS4000000.0000.000
3 C. Carroll RF4120000.5001.250
4 I. Vargas 1B1000000.0000.000
5 N. Arenado 3B4011000.2500.500
6 A. Del Castillo C4010000.2500.500
7 L. Gurriel DH3000000.0000.250
8 T. Troy LF4111101.2501.250
9 T. Tawa CF3010001.3331.000
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Wetherholt 2B4020001.5001.000
2 I. Herrera C3010010.3330.833
3 A. Burleson 1B2011010.5001.250
4 J. Walker RF4000001.0000.000
5 L. Nootbaar LF2100021.0000.500
6 M. Winn SS4110001.2500.500
7 J. Crooks DH3000000.0000.000
8 B. Jordan 3B2001000.0000.000
9 N. Church CF3121000.6671.334

D-Backs vs. Cardinals: Detailed Breakdown

Matchup Overview

  • Teams: D-Backs vs. Cardinals
  • Date: Monday, June 22, 2026
  • Time: 7:45 PM ET
  • Venue: Busch Stadium

Current Betting Odds

  • Spread: Cardinals favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: D-Backs 41¢, Cardinals 58¢

Dimers' Win Probabilities

  • D-Backs: 46%
  • Cardinals: 54%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the D-Backs a win probability of 46%, while the Cardinals have a win probability of 54%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cardinals are more likely to beat the D-Backs in the MLB game at Busch Stadium on Monday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our D-Backs vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.