Blue Jays vs. Yankees prediction: Yankees favored to win Saturday's MLB matchup [8/22/2026]
Get Toronto Blue Jays vs New York Yankees predictions for MLB Saturday.

The New York Yankees will square off with the Toronto Blue Jays, in what is expected to be a close MLB game, at Yankee Stadium on Saturday, commencing at 1:35 PM ET.
The Yankees will start Ryan Weathers (5-7, 3.56 ERA), pitting him against Dylan Cease (7-5, 2.42 ERA) for the Blue Jays.
Dimers' proven MLB model gives the Yankees a slight edge with a 50.4% win probability over the Blue Jays.
This article offers a complete Blue Jays vs. Yankees prediction, including best bets and picks.
For more, dive into Dylan Cease's projected pitching stats.
Blue Jays vs. Yankees prediction: Who will win and cover?
Our leading predictive model gives the Yankees a 50.4% chance of beating the Blue Jays.
According to our model, the Yankees (+1.5) have a 63.6% chance of covering the run line, while the 7-run over/under has a 56.2% chance of going over.
Blue Jays vs. Yankees odds [8/22/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Blue Jays -1.5 (+178) / Yankees +1.5 (-185)
- Moneyline: Blue Jays +101, Yankees +100
All odds are correct at the time of publication and are subject to change.
Blue Jays vs. Yankees picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Blue Jays -1.5 @ +178 via DraftKings
- Moneyline: Yankees @ +100 via Polymarket
- Total: Over 7 @ +110 via DraftKings
According to our MLB best bets, the top play to make on this game is Over 7 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Blue Jays vs. Yankees game-day updates and essential details
Saturday's MLB game between the Yankees and Blue Jays at Yankee Stadium is scheduled to begin at 1:35 PM ET.
- Who: Toronto Blue Jays vs. New York Yankees
- Date: Saturday, August 22, 2026
- Time: 1:35 PM ET/10:35AM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 50.4% win probability, will likely beat the Blue Jays in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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