Week 3 of the NFL season opens with a primetime divisional clash as the Buffalo Bills host the Miami Dolphins at Highmark Stadium. Alongside Dimers' predictive analytics,
Bet365
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Bet365 TNF Featured Boost:
Bet365 is giving bettors a chance to back Allen’s all-around dominance with plus-value odds:
This boost ties directly into Allen’s dual-threat profile, requiring him to excel through the air while also finding the end zone on the ground or through designed runs.
*Note: NFL odds in this article are correct at time of publication and subject to change*
Game Details: Dolphins Vs. Bills NFL Week 3
- Teams:
Miami Dolphins vs. Buffalo Bills
- Date:
Thursday, September 18, 2025
- Kickoff:
8:15 p.m. ET
- Location:
Highmark Stadium
- Spread:
Dolphins +12.5 (-110) | Bills -12.5 (-105)
- Moneyline:
Dolphins +610 | Bills -850
- Total:
O/U 49.5 (-112/-108)
Promos:
Dimers Prediction: Dolphins Vs. Bills
Dimers’ model simulated this AFC East matchup 10,000 times.
The results give the
Bills an 83% chance of victory, with Miami’s best shot coming via covering the spread, where the
Dolphins (+12.5) cover 52% of the time. The total of 49.5 points leans slightly over, with a
52% chance of going over.
Dolphins Vs. Bills Best Bet
Dimers’ top pick for Thursday Night Football is the
Dolphins moneyline (+610). Despite Buffalo being the clear favorite, simulations show a 2.8% edge on Miami compared to the sportsbook’s listed odds.
Score Prediction for Dolphins Vs. Bills
Dimers projects a final score of
Bills 30, Dolphins 19, reflecting the average result across simulations.
NFL Player Props: Dolphins Vs. Bills
Props provide additional betting intrigue beyond spreads and totals.
Miami Dolphins
- First Touchdown Scorer:
De’Von Achane (11.1%), Tyreek Hill (6.6%), Jaylen Waddle (4.6%)
- Anytime Touchdown Scorer:
Achane (50.2%), Hill (33.9%), Waddle (25.0%)
- Projected Leaders:
Tua Tagovailoa 245 passing yards, Tyreek Hill 71 receiving yards, Achane 58 rushing yards
Buffalo Bills
- First Touchdown Scorer:
James Cook (13.9%), Josh Allen (12.4%), Keon Coleman (6.0%)
- Anytime Touchdown Scorer:
Cook (58.4%), Allen (54.2%), Coleman (31.6%)
- Projected Leaders:
Josh Allen 242 passing yards, James Cook 73 rushing yards, Keon Coleman 49 receiving yards
Final Thoughts: Dolphins Vs. Bills Week 3
Thursday Night Football shines the spotlight on Buffalo’s MVP-caliber quarterback. With
focused on Josh Allen’s dual-threat production, and Dimers’ projections pointing to a Bills victory, bettors have multiple angles to consider on both sides of this AFC East rivalry.
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